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UnknownFour-year effectiveness, safety and drug retention rate of secukinumab in psoriatic arthritis: a real-life Italian multicenter cohort.
Not available
S-EPMC11438205 | biostudies-literature
TranscriptomicsSingle cell sequencing analysis of senescence in Mus musculus prostate cancer models
Acute Pten loss initiates prostate tumorigenesis characterized by cellular senescence response. Here we examine the cellular senescence response in epithelial individual cells, by single-cell RNA sequencing (scRNAseq) in Ptenpc-/- and Ptenpc-/-; Timp1-/- GEMMs. ScRNAseq analysis determines a cluste...
ORGANISM(S): Mus musculus 
2020-10-09 | E-MTAB-9578 | biostudies-arrayexpress
TranscriptomicsRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Acute Pten loss initiates prostate tumorigenesis characterized by cellular senescence response. Senescent cells secrete a variety of pro inflammatory factors in the tumor microenvironment, which can support the survival, outgrowth and migration of tumor cells. Here we examine cytokines and cytokines...
ORGANISM(S): Mus musculus 
2020-10-09 | E-MTAB-9624 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of blasts and normal cells from acute myeloid leukemia patients to study germinal copy number variants as potential disease risk factors
Except for the well-known association with Down syndrome, there is little information on the genetic factors predisposing to acute myeloid leukemia. Germinal gene copy-number variations may represent risk factors for the disease. To identify copy number variants present in both normal and leukemic ...
ORGANISM(S): Homo sapiens 
2015-10-01 | E-MTAB-2609 | biostudies-arrayexpress
TranscriptomicsMYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
MYCN is a master regulator controlling many processes necessary for tumor cell survival. Here, we unravel a microRNA network that causes tumor suppressive effects in MYCN-amplified neuroblastoma cells. In profiling studies, histone deacetylase (HDAC) inhibitor treatment most strongly induced miR-183...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-44538 | biostudies-arrayexpress
UnknownEstimated pulse wave velocity improves risk stratification for all-cause mortality in patients with COVID-19.
Not available
S-EPMC8511157 | biostudies-literature
UnknownRole of Low-Molecular-Weight Heparin in Hospitalized Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia: A Prospective Observational Study.
Not available
S-EPMC7717381 | biostudies-literature
UnknownThe NuRD component CHD3 promotes BMP signalling during cranial neural crest cell specification
Not available
S-SCDT-10_1038-S44319-025-00555-W | biostudies-other
ProteomicsMetaproteomics investigation on the gut microbiota of children affected by Autism Spectrum Disorder
Metaproteomics investigation of the Gut Microbiota in young subjects with Autism Spectrum Disorders and their relatives
ORGANISM(S): Bacteria (ncbitaxon:2) 
2020-04-06 | MSV000085232 | MassIVE
GenomicsEMseq of hiPSC, iMeLC, hPGCLC and hEGCLC of CTL08A genotype
In this work, hEGCLC have been obtained for the first time from hPGCLC in defined and feeder-free conditions. To study epigenetic changes (in terms of DNA methylation) during the transition from a pluripotent stem cell state to a germ cell identity and back again, we profiled hiPSC, iMeLC, day 6 hPG...
ORGANISM(S): Homo sapiens 
2026-02-10 | E-MTAB-15142 | biostudies-arrayexpress
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