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MetabolomicsRapid UHPLC-MS metabolite profiling and phenotypic assays reveal genotypic impacts of nitrogen supplementation in oats
INTRODUCTION: Oats (Avena sativa L.) are a whole grain cereal recognised for their health benefits and which are cultivated largely in temperate regions providing both a source of food for humans and animals, as well as being used in cosmetics and as a potential treatment for a number of...
2020-06-11 | MTBLS804 | MetaboLights
MetabolomicsAssessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches
Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties to increased nitrogen levels was investigated...
2021-04-26 | MTBLS1801 | MetaboLights
MetabolomicsMetabolomic and Proteomic Stratification of Equine Osteoarthritis

Osteoarthritis (OA) is characterised by loss of articular cartilage, synovial membrane dysfunction and subchondral sclerosis. Few studies have used a global approach to stratify equine synovial fluid (SF) molecular profiles according to OA severity. SF was collected from 58 metacarpophalangeal (M...

2025-10-16 | MTBLS1645 | MetaboLights
UnknownInsulin receptor orchestrates kidney antibacterial defenses.
Not available
S-EPMC11260129 | biostudies-literature
MetabolomicsDetermining predictive metabolomic biomarkers of meniscal injury in dogs with cranial cruciate ligament disease

OBJECTIVES: This study used hydrogen nuclear magnetic resonance spectroscopy (1H NMR) for the first-time to examine differences in the metabolomic profile of stifle joint synovial fluid from dogs with cranial cruciate ligament rupture with and without meniscal injuries, in order ...

2025-08-14 | MTBLS6050 | MetaboLights
UnknownMultimodal cortical and subcortical exercise compared with treadmill training for spinal cord injury.
Not available
S-EPMC6084979 | biostudies-literature
GenomicsDepletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding (ChIP-seq)
The t(8;21) translocation fuses the DNA binding domain of the hematopoietic master regulator RUNX1 to the ETO protein. The resultant RUNX1/ETO fusion protein is a leukemia-initiating transcription factor that interferes with RUNX1 function. The result of this interference is a block in differentiati...
ORGANISM(S): Homo sapiens 
2012-03-27 | E-GEOD-34540 | biostudies-arrayexpress
ProteomicsLocus-specific proteomics identifies CHD4 and Polycomb PRC1 as novel repressors of Epstein-Barr virus lytic reactivation
The Epstein Barr virus (EBV) is a human gammaherpesvirus which infects over 90% of the global population and is associated with lymphoid and epithelioid cancers. After infection, EBV enters a latent state in B-cells where the viral genome persists as a nuclear episome maintained by expression of a s...
ORGANISM(S): Homo sapiens (Human) 
2026-02-11 | PXD068122 | Pride
Epigenetics Virus activation Locus specific proteomics Polycomb complex Epstein-barr virus Virus latency Nurd complex De-ubiquitinase 
GenomicsDepletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding [ChIP-Seq and DNAse-Hypersensitivity data]
The t(8;21) translocation fuses the DNA binding domain of the hematopoietic master regulator RUNX1 to the ETO protein. The resultant RUNX1/ETO fusion protein is a leukemia-initiating transcription factor that interferes with RUNX1 function. The result of this interference is a block in differentiati...
ORGANISM(S): Homo sapiens 
2012-03-27 | E-GEOD-29222 | biostudies-arrayexpress
UnknownCharacterising shear-induced dynamics in flowing complex fluids using differential dynamic microscopy.
Not available
S-EPMC8513683 | biostudies-literature
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