Sort   by:  
 Page size 
UnknownDevelopment and Validation of Multivariable Machine-Learning Models for the Prediction of Multisystemic Inflammatory Syndrome Outcomes in Latin American Children.

Aim

We aimed to develop and test machine learning algorithms for the prediction of severe outcomes associated with MIS-C.

Method

An observational ambispective cohort study was conducted including children aged from 1 month to 18 years old in 84 hospitals from the REKAMLATINA (Red de l...
S-EPMC12687682 | biostudies-literature
UnknownNanoarchitecture of Ca<sub>V</sub>2.1 channels and GABA<sub>B</sub> receptors in the mouse hippocampus: Impact of APP/PS1 pathology.
Voltage-gated CaV2.1 (P/Q-type) Ca2+ channels play a crucial role in regulating neurotransmitter release, thus contributing to synaptic plasticity and to processes such as learning and memory. Despite their recognized importance in neural function, there is limited information ...
S-EPMC11835447 | biostudies-literature
UnknownReduction in the neuronal surface of post and presynaptic GABAB receptors in the hippocampus in a mouse model of Alzheimer's disease.
The hippocampus plays key roles in learning and memory and is a main target of Alzheimer's disease (AD), which causes progressive memory impairments. Despite numerous investigations about the processes required for the normal hippocampal functions, the neurotransmitter receptors involved in the syna...
S-EPMC7317930 | biostudies-literature
UnknownAge-Dependent Shift of AMPA Receptors From Synapses to Intracellular Compartments in Alzheimer's Disease: Immunocytochemical Analysis of the CA1 Hippocampal Region in APP/PS1 Transgenic Mouse Model.
Synapse loss occurs early in Alzheimer's disease (AD) patients and animal models. Alterations at synaptic level are a major morphological correlate of the memory deficits and related symptoms of AD. Given the predominant roles of synaptic AMPA receptors (AMPARs) in excitatory synaptic transmission i...
S-EPMC7572859 | biostudies-literature
UnknownSupercritical CO2 Processing of White Grape Must as a Strategy to Reduce the Addition of SO2.
In winemaking, sulfur dioxide addition is the most common procedure to prevent enzymatic and microbial alterations. However, the enological industry looks for safer alternatives to preserve enological products, and high-pressure treatments with supercritical CO2 are a suitable alternative...
S-EPMC10453421 | biostudies-literature
UnknownDetermining the Optimal Conditions for the Production by Supercritical CO2 of Biodegradable PLGA Foams for the Controlled Release of Rutin as a Medical Treatment.
Poly(D,L,-lactide-co-glycolide) (PLGA) foam samples impregnated with rutin were successfully produced by supercritical foaming processes. A number of parameters such as pressure (80-200 bar), temperature (35-55 °C), depressurization rate (5-100 bar/min), ratio lactide:glycolide of the poly(D,L,-lact...
S-EPMC8158779 | biostudies-literature
UnknownFoaming of Polycaprolactone and Its Impregnation with Quercetin Using Supercritical CO2.
Foamed polycaprolactone impregnated with quercetin was carried out with a batch foaming technique using supercritical CO2. The experimental design was developed to study the influence of pressure (15-30 MPa), temperature (308-333 K), and depressurization rate (0.1-20) on the foam structure, melting ...
S-EPMC6780592 | biostudies-literature
UnknownImplementation of a retinal stroke-code protocol results in visual recovery in patients receiving reperfusion therapies.

Introduction

Reperfusion therapies represent promising treatments for patients with Central Retinal Artery Occlusion (CRAO), but access is limited due to low incidence and lack of protocols. We aimed to describe the benefit of implementing a Retinal Stroke-Code protocol regarding access to r...
S-EPMC11318432 | biostudies-literature
UnknownKey Factors Associated With Pulmonary Sequelae in the Follow-Up of Critically Ill COVID-19 Patients.

Introduction

Critical COVID-19 survivors have a high risk of respiratory sequelae. Therefore, we aimed to identify key factors associated with altered lung function and CT scan abnormalities at a follow-up visit in a cohort of critical COVID-19 survivors.

Methods

Multicenter ambispect...
S-EPMC9824938 | biostudies-literature
UnknownMolecular detection of Rickettsia felis in different flea species from Caldas, Colombia.
Rickettsioses caused by Rickettsia felis are an emergent global threat. Historically, the northern region of the province of Caldas in Colombia has reported murine typhus cases, and recently, serological studies confirmed high seroprevalence for both R. felis and R. typhi. In the present study, flea...
S-EPMC3771280 | biostudies-literature
Sort   by:  
 Page size