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TranscriptomicsTranscription profiling of mouse T cell response to ocular pigment epithelial cells - role of thrombospondin 1
Ocular pigment epithelium (PE) cells promote the generation of T regulators (PE-induced Treg cells). Moreover, T cells exposed to PE acquire the capacity to suppress the activation of bystander T cells via TGFbeta. Membrane-bound TGFbeta on iris PE cells interacts with TGFbeta receptors on T cells, ...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5134 | biostudies-arrayexpress
TranscriptomicsThe Menin-Bach2 axis is critical for regulating CD4 T cell senescence and cytokine homeostasis
Although CD4 T cell senescence plays an important role in immunosenescence, the mechanism behind this process remains unclear. Here we show that T cell-specific Menin deficiency results in the premature senescence of CD4 T cells, which is accompanied by the senescence-associated secretory phenotype...
ORGANISM(S): Mus musculus 
2014-03-27 | E-GEOD-49968 | biostudies-arrayexpress
MetabolomicsUnique metabolic regulation of micromeres contributes to their inductive signaling in the sea urchin embryo

In many multicellular organisms, a group of cells called organizers plays critical roles by sending signals to adjacent cells and controlling patterning events such as embryogenesis and tissue morphogenesis. Recent studies suggest that these organizers or inductive cells facilitate the downstream...

2025-07-07 | MTBLS5017 | MetaboLights
UnknownTrained murine mesenchymal stem cells have anti-inflammatory effect on macrophages, but defective regulation on T-cell proliferation.
Not available
S-EPMC6629132 | biostudies-literature
UnknownDendritic cells from oral cavity induce Foxp3(+) regulatory T cells upon antigen stimulation.
Not available
S-EPMC3525649 | biostudies-literature
UnknownControl of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3.
Not available
S-EPMC3140164 | biostudies-literature
UnknownCADM1 interacts with Tiam1 and promotes invasive phenotype of human T-cell leukemia virus type I-transformed cells and adult T-cell leukemia cells.
Not available
S-EPMC2865322 | biostudies-literature
UnknownMutation of inhibitory helix-loop-helix protein Id3 causes γδ T-cell lymphoma in mice.
Not available
S-EPMC3031408 | biostudies-literature
UnknownClinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes.
Not available
S-EPMC4442500 | biostudies-literature
UnknownThe Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis.
Not available
S-EPMC3988815 | biostudies-literature
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