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TranscriptomicsGene expression profiling of Human Umbilical Vein Endothelial Cells (HUVEC) after treatment with Erg or control antisense (GeneBloc)
The endothelial transcription factor Erg (Ets Related Gene) plays an important role in homeostasis and angiogenesis by regulating many endothelial functions including survival and junction stability. Here we show that Erg regulates endothelial cell migration. Transcriptome profiling of Erg-deficient...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-32984 | biostudies-arrayexpress
UnknownInvestigation of a dilated cardiomyopathy-associated variant in BAG3 using genome-edited iPSC-derived cardiomyocytes.
Not available
S-EPMC6948852 | biostudies-literature
TranscriptomicsTranscription profiling of human WT1-mutant versus WT1 wild-type Wilms tumors
Gain-of-function mutations in exon 3 of beta-catenin (CTNNB1) are specific for Wilms' tumors that have lost WT1, but 50% of WT1-mutant cases lack such "hot spot" mutations. To ask whether stabilization of beta-catenin might be essential after WT1 loss, and to identify downstream target genes, we com...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6120 | biostudies-arrayexpress
UnknownUCART19, a first-in-class allogeneic anti-CD19 chimeric antigen receptor T-cell therapy for adults with relapsed or refractory B-cell acute lymphoblastic leukaemia (CALM): a phase 1, dose-escalation trial.
Not available
S-EPMC11575699 | biostudies-literature
UnknownGenome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies.
Not available
S-EPMC11773457 | biostudies-literature
UnknownClinical characteristics, racial inequities, and outcomes in patients with breast cancer and COVID-19: A COVID-19 and cancer consortium (CCC19) cohort study.
Not available
S-EPMC10637772 | biostudies-literature
GenomicsWhole Genome Sequencing of a Triple Negative Breast Cancer Patient: Matched Primary Tumor, Normal, Metastasis and Xenograft samples

Breast Cancer Subject Participant ID 700064 (Source Sample names: 6888 and 206). We used massively parallel DNA sequencing technologies to screen entire genomes, in an unbiased manner, for genetic changes associated with tumor growth and metastasis. We describe the complete genome sequence ...

phs000245.v1.p1 | EGA
UnknownDevelopment and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair.
Not available
S-EPMC12267650 | biostudies-literature
UnknownDevelopment and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair.
Not available
S-EPMC11429686 | biostudies-literature
UnknownResource profile and user guide of the Polygenic Index Repository.
Not available
S-EPMC8678380 | biostudies-literature
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