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UnknownPatients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial.
Not available
S-EPMC5015426 | biostudies-literature
TranscriptomicsPatients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial
The AVAglio and RTOG-0825 randomized, placebo-controlled phase III trials in newly diagnosed glioblastoma reported prolonged progression-free survival (PFS), but not overall survival (OS), with the addition of bevacizumab to radiotherapy/temozolomide. To establish whether certain patient subgroups d...
ORGANISM(S): Homo sapiens 
2016-07-06 | E-GEOD-84010 | biostudies-arrayexpress
TranscriptomicsTranscriptome comparison of bat (Miniopterus natalensis) forelimb and hindlimb autopods at developmental stages CS16 and CS17 and E13.5 mouse forelimb autopods
The bat offers an alternative paradigm to the standard mouse and chick model of limb development as it has extremely divergent forelimbs (long digits supporting a wing) and hindlimbs (short digits and claws) due the distinct requirements of both aerial and terrestrial locomotion. We used a cross-spe...
ORGANISM(S): Mus musculus 
2014-02-15 | E-GEOD-51042 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of Human Umbilical Vein Endothelial Cells (HUVEC) after treatment with Erg or control antisense (GeneBloc)
The endothelial transcription factor Erg (Ets Related Gene) plays an important role in homeostasis and angiogenesis by regulating many endothelial functions including survival and junction stability. Here we show that Erg regulates endothelial cell migration. Transcriptome profiling of Erg-deficient...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-32984 | biostudies-arrayexpress
GenomicsItalian Primary Biliary Cirrhosis Study

A Genome-wide association study of primary biliary cirrhosis (PBC) with an Italian cohort and loci meeting suggestive criteria were confirmed using a replication dataset from a previous Canadian study. The results confirmed associations for IL12A, IL12RB2, and HLA (peak between DQA1 and DQB1) and...

phs000444.v1.p1 | EGA
UnknownNMDA receptor gene variations as modifiers in Huntington disease: a replication study.
Not available
S-EPMC3186947 | biostudies-literature
UnknownFatal and Nonfatal Events Within 14 days After Early, Intensive Mobilization Poststroke.
Not available
S-EPMC8055346 | biostudies-literature
UnknownLarge-scale migration into Britain during the Middle to Late Bronze Age.
Not available
S-EPMC8889665 | biostudies-literature
UnknownEmpagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10957483 | biostudies-literature
UnknownTocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8084355 | biostudies-literature
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