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ProteomicsiPOND mass sepctrometry (iPOND-MS) in BRCA1-A complex deficient cells treated with CPT in combination with an ATM inhibitor
iPOND Mass spectrometry (iPOND-MS) was performed to identify replication fork proteome in wild type (WT) and ABARAXAS KO (ABX KO) HEK293T cells treated with 1 µM CPT in combination with 250 nM ATM inhibitor (AZD0156). An additional set of control cells were kept for no-click (NC) negative control. T...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD077767 | Pride
ProteomicsCharacterization of circulating extracellular vesides of steroid sensitive nephrotic syndrome patients
plasma extracellular vesicles of 8 petients and 4 healty controls were studied by mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD024217 | Pride
Nephrotic syndrome Extracellular vesides 
ProteomicsThe role and cooperation of AidB dehydrogenase and AlkB dioxygenase in repair of adducts to DNA and RNA bases
The aim of the project is to conduct in vivo, in vitro and in silico studies of the substrate specificity of AidB dehydrogenase against the by-products rising in AlkB dioxygenase repair reaction and AlkB and AidB cooperative interaction in the repair of adducts to DNA and RNA bases. AidB dehydrogena...
ORGANISM(S): Escherichia coli 
2025-05-07 | PXD057294 | Pride
Aidb dehydrogenase Dna repair Alkb dioxygenase E.coli Rna repair 
ProteomicsComparative maternal protein profiling of mouse biparental and uniparental embryos
During oogenesis, RNAs and proteins from maternal genome will be accumulated and they are the most important regulatory factors in early embryonic development. Parthenogenesis provides a unique source to investigate the influence of maternal genomes in early mammalian development and is proposed as ...
ORGANISM(S): Homo Sapiens Mus Musculus 
2022-07-15 | PXD029532 |
UnknownAutologous micrograft accelerates endogenous wound healing response through ERK-induced cell migration.
Not available
S-EPMC7206041 | biostudies-literature
ProteomicsEngineered Extracellular Vesicles Prepared by Membrane Extrusion Are Good Substitutes for Natural Extracellular Vesicles
Extracellular vesicles (EV) as drug delivery nanocarriers are under intense investigation. Although clinical-grade EVs have been produced on a large-scale, low yield and high production costs of natural EVs (nEV) limit the relevant industrial translation. Recent studies show that mechanical extrusio...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD030826 | Pride
Mass sepctrometry Drug delivery Extracellular vesicles Next generation sequecing Engineered vesicles 
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