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TranscriptomicsTime-of-day-dependent light-induction of gene expression in the chicken pineal gland
Light has a strong effect on whole organism physiology, such as the circadian rhythms that are phase delayed and advanced by light given at early and late subjective night, respectively. Despite the importance of the phase-dependent light responses, little is known about the underlying molecular mec...
ORGANISM(S): Gallus gallus 
2011-03-08 | E-GEOD-21915 | biostudies-arrayexpress
TranscriptomicsReprogramming-associated aberrant DNA methylation determines hematopoietic differentiation capacity of human induced pluripotent stem cells [iPSC_ESC_lines]
The variation among induced pluripotent stem cells (iPSCs) in their differentiation capacity to specific lineages is frequently attributed to somatic memory. In this study, we compared hematopoietic differentiation capacity of 35 human iPSC lines derived from four different tissues and four embryoni...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-75096 | biostudies-arrayexpress
TranscriptomicsMurine Ba/F3 Cells: Ba/F3 cells expressing wild type JAK2 (WT cells) vs. Ba/F3 cells expressing JAK2 V617F mutant (VF cells)
Transcriptional profiling of transformed Ba/F3 cells by myeloproliferative neoplasm-associated JAK2 V617F mutant comparing control Ba/F3 cells expressing wild type JAK2. Two-condition experiment, WT cells vs. VF cells. One replicate per array.
ORGANISM(S): Mus musculus 
2013-10-31 | E-GEOD-34239 | biostudies-arrayexpress
TranscriptomicsReprogramming-associated aberrant DNA methylation determines hematopoietic differentiation capacity of human induced pluripotent stem cells [Human pluripotent stem cells-derived hematopoietic precursor cells]
The variation among induced pluripotent stem cells (iPSCs) in their differentiation capacity to specific lineages is frequently attributed to somatic memory. In this study, we compared hematopoietic differentiation capacity of 35 human iPSC lines derived from four different tissues and four embryoni...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-60810 | biostudies-arrayexpress
TranscriptomicsReprogramming-associated aberrant DNA methylation determines hematopoietic differentiation capacity of human induced pluripotent stem cells [Erythroid_lines]
The variation among induced pluripotent stem cells (iPSCs) in their differentiation capacity to specific lineages is frequently attributed to somatic memory. In this study, we compared hematopoietic differentiation capacity of 35 human iPSC lines derived from four different tissues and four embryoni...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-75095 | biostudies-arrayexpress
TranscriptomicsReprogramming-associated aberrant DNA methylation determines hematopoietic differentiation capacity of human induced pluripotent stem cells [iPS_derived_erythroiblasts]
The variation among induced pluripotent stem cells (iPSCs) in their differentiation capacity to specific lineages is frequently attributed to somatic memory. In this study, we compared hematopoietic differentiation capacity of 35 human iPSC lines derived from four different tissues and four embryoni...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-60922 | biostudies-arrayexpress
TranscriptomicsOverexpression of NUCKS1 in colorectal cancer correlates with recurrence after curative surgery (copy number analysis)
Purpose: The purpose of this study is to identify a novel biomarker related with distant metastases of colorectal cancer (CRC). Experimental Design: We investigated mRNA expression profiles in 115 patients with CRC using an Affymetrix Gene Chip, and copy number profiles in 122 patients with CRC usin...
ORGANISM(S): Homo sapiens 
2012-10-16 | E-GEOD-27910 | biostudies-arrayexpress
TranscriptomicsOverexpression of NUCKS1 in colorectal cancer correlates with recurrence after curative surgery (gene expression analysis)
Purpose: The purpose of this study is to identify a novel biomarker related with distant metastases of colorectal cancer (CRC). Experimental Design: We investigated mRNA expression profiles in 115 patients with CRC using an Affymetrix Gene Chip, and copy number profiles in 122 patients with CRC usin...
ORGANISM(S): Homo sapiens 
2012-10-16 | E-GEOD-27854 | biostudies-arrayexpress
TranscriptomicsPrognostic significance of overexpression of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer [gene expression]
Introduction: The potential of expression profiling using microarray analysis as a tool to predict the prognosis for different types of cancer has been realized. This study aimed to identify a novel biomarker for colorectal cancer (CRC). Experimental design: The expression profiles of cancer cells ...
ORGANISM(S): Homo sapiens 
2015-11-21 | E-GEOD-64256 | biostudies-arrayexpress
TranscriptomicsPrognostic significance of overexpression of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer [copy number analysis]
Introduction: The potential of expression profiling using microarray analysis as a tool to predict the prognosis for different types of cancer has been realized. This study aimed to identify a novel biomarker for colorectal cancer (CRC). Experimental design: The expression profiles of cancer cells ...
ORGANISM(S): Homo sapiens 
2015-11-21 | E-GEOD-64257 | biostudies-arrayexpress
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