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TranscriptomicsMiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer from never-smokers
Approximately 15% of lung cancer cases are not associated with smoking and show molecular and clinical characteristics distinct from those in smokers. Epidermal growth factor receptor (EGFR) gene mutations, which are correlated with sensitivity to EGFR-tyrosine kinase inhibitors (EGFR-TKIs), are mo...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-14936 | biostudies-arrayexpress
TranscriptomicsPaired non-cancerous and cancerous miRNA expression of esophageal adenocarcinoma and squamous cell carcinoma patients
Identifying biomarkers predictive for early esophageal cancer detection is critical considering the dismal survival rates. We investigated the involvement of microRNAs (miRNAs), their utility as biomarkers, and their association with survival in esophageal cancer, including Barrett’s associated and...
ORGANISM(S): Homo sapiens 
2010-07-09 | E-GEOD-13937 | biostudies-arrayexpress
MetabolomicsNon-invasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer
Lung cancer remains the most common cause of cancer deaths worldwide, yet there is currently a lack of diagnostic noninvasive biomarkers that could guide treatment decisions. Small molecules (<1500 Da) were measured in urine collected from 469 lung cancer patients and 536 population controls using u...
2014-05-06 | MTBLS28 | MetaboLights
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