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Background Probiotics have attracted considerable interest for ulcerative colitis (UC); however, their efficacy is highly strain-specific and the underlying molecular mechanisms remain incompletely understood.

Results Accumulating evidence indicates that bacterial extracellular vesicles (BE...

2026-01-23 | MTBLS13753 | MetaboLights
This study performs untargeted metabolomics analysis on intestinal tissues of DSS-induced colitis zebrafish models to uncover the metabolic regulatory mechanisms of AmEVs. We compared intestinal metabolite profiles between two experimental groups: DSS-induced colitis model group and AmEV interventio...
2026-07-22 | MTBLS14855 | MetaboLights
To better understand the mechanism underlying the invasion and migration phenotype instigated by EFEMP1 EVs (extracellular vesicles), we performed RNA sequencing analysis on BT549 cells treated with control and EFEMP1KD EVs.
ORGANISM(S): Homo sapiens 
Comprehensive analysis of miRNAs in matrix vesicles

BACKGROUND: Ochratoxin A (OTA) have made it a serious hazard to food safety worldwide that poses a serious health risk to humans. Our previous research showed that Walnut green husk polysaccharides (WGP) can effectively alleviate intestinal inflammation and intestinal microbiota ...

2024-10-10 | MTBLS10673 | MetaboLights
Phenotypic changes induced by extracellular vesicles (EVs) have been implicated in the recovery of acute kidney injury (AKI) induced by mesenchymal stromal cells (MSCs). miRNAs are potential candidates for cell reprogramming towards a pro-regenerative phenotype. The aim of the present study was to e...
ORGANISM(S): Mus musculus 
Analysis of GPM6B silenced osteogenic hMSC at gene expression level. Analysis is showing significant changes in genes involved in cytoskeleton organization and biogenesis. Immunocytochemistry confirms changed distribution of actin filaments and change in shape and in size of focal adhesions upon GP...
ORGANISM(S): Homo sapiens 
The endosomal FYVE- and WD40-domain-containing protein WDFY2 has been assigned a function as tumor suppressor, but its functional mechanism has remained elusive. Here we have used confocal, widefield and super-resolution fluorescence microscopy to show that WDFY2 localizes to the base of retromer-co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-23 | MSV000084122 | MassIVE
1α,25-Dihydroxyvitamin D3 Regulates Packaging of microRNAs within Extracellular Matrix Vesicles and Their Release in the Matrix
miRNAs in matrix vesicles isolated from the extracellular matrix of MC3T3-E1 cell cultures
ORGANISM(S): Mus musculus 
2019-11-13 | GSE140242 | GEO
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