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ALKBH5-mediated m6A demethylation ameliorates extracellular matrix deposition in cutaneous pathological fibrosis [meRIP-seq]
Hypertrophic scars (HTS) are fibrotic skin disorders characterized by excessive deposition of dermal extracellular matrix (ECM), presenting significant challenges in clinical management despite incomplete understanding of their underlying mechanisms. Using MeRIP-seq and RNA-seq, our study initially ...
ORGANISM(S): Homo sapiens 
2024-09-13 | GSE264743 | GEO
MultiomicsTracks96: A high throughput PIXUL-Matrix-based toolbox to profile frozen and FFPE tissues multiomics (MeRIP-Seq)
Background: The multiome is an integrated assembly of distinct classes of molecules and molecular properties, or “omes,” measured in the same biospecimen. Freezing and formalin-fixed paraffin-embedding (FFPE) are two common ways to store tissues, and these practices have generated vast biospecimen r...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-14 | PXD041462 | Pride
Hypertrophic scars (HTS) are fibrotic skin disorders characterized by excessive deposition of dermal extracellular matrix (ECM), presenting significant challenges in clinical management despite incomplete understanding of their underlying mechanisms. Using MeRIP-seq and RNA-seq, our study initially ...
ORGANISM(S): Homo sapiens 
2024-09-13 | GSE264515 | GEO
To identify the m6A methylome in the aorta of patients with acute aortic dissection. MeRIP-seq and RNA-seq experiments of aortic media tissue samples obtained from AD patients and controls were conducted. Compared with control group, the upmethylated coding genes of AD were primarily enriched in the...
ORGANISM(S): Homo sapiens 
2020-03-17 | GSE147026 | GEO
To identify the m6A methylome in the aorta of patients with acute aortic dissection. MeRIP-seq and RNA-seq experiments of aortic media tissue samples obtained from AD patients and controls were conducted. Compared with control group, the upmethylated coding genes of AD were primarily enriched in the...
ORGANISM(S): Homo sapiens 
2020-03-17 | GSE147027 | GEO
Integration of ChIP, MeDIP, MeRIP, and RT Seq for multiomics analysis of frozen and FFPE tissue
ORGANISM(S): Mus musculus 
2024-01-06 | GSE230103 | GEO
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