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MetabolomicsUntargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma
Neuroblastoma (NB) is the most common extracranial malignant tumor in children. Although the survival rate of NB has improved over the years, the outcome of NB still remains poor for over 30% of cases. A more accurate risk stratification remains a key point in the study of NB and the availability of...
2023-07-14 | MTBLS4294 | MetaboLights
UnknownPhase I Study of the Aurora A Kinase Inhibitor Alisertib in Combination With Irinotecan and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma: A NANT (New Approaches to Neuroblastoma Therapy) Trial.
Not available
S-EPMC4872349 | biostudies-literature
ProteomicsQuantitative proteomics and bioinformatics analyses reveal the mechanism of pan-aurora kinase inhibitor tozasertib in neuroblastoma
Neuroblastoma is the third most common pediatric cancer and is responsible for approximately 15% of all childhood cancer deaths (Maris & Matthay, 1999). In our analysis, we found that poor patient survival with increasing mRNA expression level of AURKA and AURKB in Mycn-amplified neuroblastoma. In t...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-09-30 | PXD007640 | Pride
Neuroblastoma/ tozasertib/ itraq/ metabolite/ aurora kinase inhibitor. 
UnknownMitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS.
Not available
S-EPMC4982045 | biostudies-literature
UnknownAscorbate for Organ Dysfunction in Critically Ill Patients With Sepsis: The Phase 2b ASTER Trial.
Not available
S-EPMC12823136 | biostudies-literature
UnknownThe utility of clinical predictors of acute lung injury: towards prevention and earlier recognition.
Not available
S-EPMC3044497 | biostudies-literature
UnknownBiomarkers for Acute Respiratory Distress syndrome and prospects for personalised medicine.
Not available
S-EPMC6332898 | biostudies-literature
UnknownClinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma.
Not available
S-EPMC3675667 | biostudies-literature
UnknownOutcome after surgery alone or with restricted use of chemotherapy for patients with low-risk neuroblastoma: results of Children's Oncology Group study P9641.
Not available
S-EPMC3383182 | biostudies-literature
UnknownMesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial.
Not available
S-EPMC4297579 | biostudies-literature
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