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TranscriptomicsNuclear Factor I/B is an Oncogene in Small Cell Lung Cancer
Small cell lung cancer (SCLC) is an aggressive cancer often diagnosed only after it has metastasized to distant sites (Meuwissen and Berns 2005; Cooper and Spiro 2006). Despite the need to better understand this disease, SCLC remains poorly characterized at the molecular and genomic levels (Forgacs ...
ORGANISM(S): Mus musculus 
2011-12-08 | E-GEOD-29533 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human A549 cell line treated with type I and II interferons vs. controls
Type I and type II interferons (IFNs) bind to different cell surface receptors but activate overlapping signal transduction pathways. We examined the effects of a type I IFN (IFN-acon1) and a type II iFN (IFN-g1b) on gene experession in A549 cells and demonstrate that there is a common set of genes ...
ORGANISM(S): Homo sapiens 
2007-11-02 | E-GEOD-5542 | biostudies-arrayexpress
TranscriptomicsGlobal transcriptome of CFA/I expressing ETEC H10407 under in vitro growth and water stress
Enterotoxigeneic Escherichia coli (ETEC) is a leading cause of diarrhoeal infections in young children living in endemic regions in low and middle-income countries and adults travelling to these destinations. CFA/I fimbriae have been identified as the predominant colonisation factor associated with ...
ORGANISM(S): Escherichia coli ETEC H10407 
2021-04-21 | E-MTAB-9364 | biostudies-arrayexpress
TranscriptomicsMapping of cohesion factor association sites in S. cerevisiae - Meiosis I chromosome segregation is established through regulation of microtubule-kinetochore interactions.
During meiosis, a single round of DNA replication is followed by two consecutive rounds of nuclear divisions called meiosis I and meiosis II. In meiosis I, homologous chromosomes segregate, while sister chromatids remain together. Determining how this unusual chromosome segregation behavior is estab...
ORGANISM(S): Saccharomyces cerevisiae 
2012-10-05 | E-GEOD-41339 | biostudies-arrayexpress
GenomicsRNA-seq reveals genes regulated by type I interferon during Rickettsia infection in WT and Irf-deficient bone marrow-derived macrophages
RNA-seq reveals genes regulated by type I interferon during Rickettsia infection in WT and Irf-deficient bone marrow-derived macrophages
PRJNA526887 | ENA
TranscriptomicsEndogenous, tissue-specific short-interfering RNAs silence the chalcone synthase gene family in Glycine max seed coats
We present results from deep sequencing of small RNA populations from several genotypes of soybean and demonstrate that the CHS siRNAs accumulated only in the seed coats of the yellow varieties having either the dominant I or i-i alleles and not in the pigmented seed coats with homozygous recessive ...
ORGANISM(S): Glycine max 
2010-05-13 | E-GEOD-21825 | biostudies-arrayexpress
ProteomicsElucidation of Proteostasis Defects Caused by Osteogenesis Imperfecta Mutations in the Collagen-A2(I) C-Propeptide Domain; Doan et al.
Data set containing interaction data of wt and mutated C-Propeptide domain of Collagen-A2(I), analyzed on Thermo QE, ProteomeDiscoverer and Scaffold
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-27 | MSV000085340 | MassIVE
ProteomicsHs_C-HPP_DentalPulpTails_N-terminomics
Hs_C-HPP, dental pulp proteome, TAILS technique
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005343 | PeptideAtlas
TranscriptomicsTranscription profiling of human naive CD8 T cells at 0, 24, 48 and 72h of in vitro culture stimulated with antigen-B7 and with or without IL-12 or IFNa/b
Differentiation of naive CD8 T cells into cytotoxic effector cells requires three distinct signals- antigen (signal 1), costimulation -B7-1 (signal 2) and cytokine, either interleukin-12 or interferon-a/b (signal 3). Interaction of naive CD8 T cells with antigen and B7-1 programs cell division and p...
ORGANISM(S): Mus musculus 
2009-08-01 | E-GEOD-15930 | biostudies-arrayexpress
ProteomicsSelenoprotein I is indispensable for ether lipid homeostasis and proper myelination
Selenoprotein I (SELENOI) catalyzes the final reaction of the CDP-ethanolamine branch of the Kennedy pathway, generating the phospholipids phosphatidylethanolamine (PE) and plasmenyl-PE. Plasmenyl-PE is a key component of myelin and is characterized by a vinyl ether bond that preferentially reacts w...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-04-03 | MSV000094464 | MassIVE
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