Maturation medium

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Transcriptomics (901)
Unknown (673)
Genomics (297)
Proteomics (125)
Metabolomics (23)
Models (2)
Methylation profiling (2)
Genomic (1)

Organisms

Homo sapiens (460)
Mus musculus (249)
Bos taurus (54)
Arabidopsis thaliana (26)
Drosophila melanogaster (23)
Rattus norvegicus (11)
Saccharomyces cerevisiae (9)
Gallus gallus (8)
Sus scrofa (8)
Schizosaccharomyces pombe (7)
Danio rerio (6)
Oryza sativa (5)
Candida albicans (5)
Mytilus galloprovincialis (4)
Mycolicibacterium smegmatis MC2 155 (4)
Caenorhabditis elegans (4)
Escherichia coli (4)
Bacillus subtilis subsp. subtilis str. 168 (3)
Macaca mulatta (3)
Streptomyces venezuelae (3)
Escherichia coli K-12 (3)
Dictyostelium discoideum AX2 (2)
Larix kaempferi (2)
Schizophyllum commune (2)
Gossypium hirsutum (2)
Mycolicibacterium smegmatis (2)
Brugia pahangi (2)
Schistosoma mansoni (2)
Medicago truncatula (2)
Zea mays (2)

Organisms

Homo sapiens (97)
Mus musculus (54)
Bos taurus (23)
Sus scrofa (7)
Arabidopsis thaliana (4)
Ovis aries (3)
Larix kaempferi (2)
Mytilus galloprovincialis (2)
Rattus norvegicus (2)
Danio rerio (2)
Adenoviridae (1)
Anguilla anguilla (1)
Dorcoceras hygrometricum (1)
Mycobacterium avium subsp. paratuberculosis K-10 (1)
Sthenoteuthis oualaniensis (1)
Pinus pinaster (1)
Caulobacter vibrioides (1)
Streptomyces coelicolor (1)
Synechocystis sp. PCC 6803 (1)
Mycosarcoma maydis (1)
Mus musculus domesticus (1)
Saccharina japonica (1)
Candida albicans (1)
Solanum lycopersicum (1)

Repository

biostudies-arrayexpress (893)
ENA (230)
pride (120)
geo (77)
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Tissue

Cell culture (32)
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Oocyte (7)
Blood (6)
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Disease

Normal (4)
Disease free (4)
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Carcinoma (1)
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Female reproductive system (1)
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Lysosomal storage disease (1)
Male infertility (1)
Multiple myeloma (1)
Neurodegenerative disease (1)
Plasmodium falciparum malaria (1)
Recessive dystrophic epidermolysis bullosa (1)
Trypanosomiasis (1)

Technology Type

Mass Spectrometry (120)
Shotgun proteomics (75)
Bottom-up proteomics (23)
Mass spectrometry (16)
Affinity purification coupled with mass spectrometry proteomics (15)
Data-dependent acquisition (12)
Mass spectrometry assay (7)
Gel-based experiment (6)
HDMSE (6)
SWATH MS (5)
Data-independent acquisition (4)
NMR spectroscopy (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
Immunopeptidomics (1)

Instrument Platform

Illumina NovaSeq 6000 (39)
Illumina HiSeq 2500 (20)
NextSeq 500 (20)
Illumina HiSeq 2000 (14)
Illumina HiSeq 4000 (13)
NextSeq 550 (10)
Affymetrix GeneChip Scanner 3000 7G (7)
NextSeq 2000 (5)
PromethION (3)
Single-Cell Extraction: For enzymatic digestion, pronase (Septomyces argeus, 1 mg/mL) was applied for 25 minutes at room temperature for P0 to P8 datasets. Cells were dissociated and triturated into a single-cell suspension in ACSF supplemented with 1% fetal calf serum (FCS) and DNase (1 µL/10 mL). Trituration was performed using three glass Pasteur pipettes of decreasing diameters. For P30 datasets, enzymatic digestion and cell dissociation were carried out using the Worthington Papain Dissociation System, following the manufacturer’s instructions. Single-Nuclei Extraction: For nuclei isolation, the Hibernate™-E Medium was removed, and 500 µL of chilled 0.1X NP40 Lysis Buffer was added. Tissue was homogenized using a Pellet Pestle (15 strokes) and incubated on ice for 5 minutes. The suspension was pipette-mixed 10 times using a wide-bore pipette tip and incubated for an additional 10 minutes on ice. Following lysis, 500 µL of chilled wash buffer was added, and the mixture was pipette-mixed 5 times using a regular-bore pipette tip. The suspension was filtered through a 30 µm cell strainer into a 50 mL tube to remove debris. The filtered suspension was transferred to a 1.5 mL tube and centrifuged at 950 × g for 10 minutes at 4°C. The supernatant was carefully removed, and the nuclei pellet was retained for downstream analysis. (2)
Element AVITI (2)
G2565AA DNA microarray scanner [Agilent] (2)
418 [Affymetrix] (2)
ScanArray Express HT (2)
Illumina NovaSeq X (2)
NA (2)
Illumina HiSeq 1500 (2)
Illumina HiSeq 3000 (2)
Chromium Next GEM Chip G (1)
10X v3 (1)
Faxitron 43855-D irradiator (1)
Single nuclei were captured using the 10x Genomics Chromium Controller. (1)
Thermocycler; SPRI magnetic bead rack; Qubit fluorometer; Agilent Bioanalyzer (1)
Branson Digital Sonifier; refrigerated benchtop centrifuge; rotator; magnetic rack (1)
Controlled-environment growth chambers (long-day and short-day) (1)
Dissection tools; liquid nitrogen; −80 °C freezer (1)
Cutadapt, STAR (1)
TruSeq Stranded mRNA Sample Prep Kit (Illumina) (1)
BD InFlux Cytometer (Becton-Dickinson) (1)
MACS (1)

Publication Date

2014 (125)
2015 (104)
2013 (97)
2012 (96)
2016 (83)
2011 (81)
2010 (81)
2025 (72)
2026 (50)
2023 (42)
2024 (40)
2008 (39)
2009 (35)
2022 (31)
2018 (24)
2007 (24)
2020 (23)
2019 (23)
2021 (21)
2017 (16)
2006 (6)
2005 (3)
2004 (2)
2003 (1)

CHEBI ID

CHEBI:17053 (5)
CHEBI:17858 (5)
CHEBI:16027 (5)
CHEBI:16015 (5)
CHEBI:16704 (5)
CHEBI:17895 (5)
CHEBI:17196 (4)
CHEBI:16856 (4)
CHEBI:15676 (4)
CHEBI:15727 (4)
CHEBI:15891 (4)
CHEBI:16335 (4)
CHEBI:17750 (4)
CHEBI:17562 (4)
CHEBI:16349 (4)
CHEBI:7916 (4)
CHEBI:18012 (4)
CHEBI:16761 (4)
CHEBI:17345 (4)
CHEBI:32805 (4)
CHEBI:16708 (4)
CHEBI:18050 (4)
CHEBI:15741 (4)
CHEBI:17172 (4)
CHEBI:17115 (4)
CHEBI:16737 (4)
CHEBI:16919 (4)
CHEBI:52071 (2)
CHEBI:37926 (2)
CHEBI:52083 (2)

Metabolite Name

Uridine (5)
Creatinine (5)
Betaine (4)
Adenosine 5'-monophosphate (4)
Choline (4)
N-Acetylneuraminic acid (4)
Cis-Aconitic acid (4)
Cytosine (4)
L-Tryptophan (4)
L-Glutamine (4)
Cytidine (4)
Guanosine (4)
Creatine (4)
Glycerophosphocholine (4)
L-Carnitine (4)
L-Tyrosine (4)
L-Phenylalanine (4)
Hypoxanthine (4)
Alanine (3)
Argininosuccinic acid (3)
Pro-Asp (3)
L-Proline (3)
L-Lysine (3)
Thiamine (3)
N-Acetyl-L-methionine (3)
Ornithine (3)
D-Erythrose 4-phosphate (3)
L-Arginine (3)
Pyridoxine (3)
Pantothenic acid (3)

First Public Date

2025 (39)
2014 (36)
2024 (32)
2026 (27)
2023 (19)
2022 (14)
2015 (12)
2021 (11)
2018 (11)
2020 (8)
2019 (7)
2017 (7)
2013 (4)
2016 (3)

Modelling Approach

Ordinary differential equation model (2)

Lab affiliation

Laboratório de Biotecnologia, Centro de Biociências e Biotecnologia (CBB), Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF), Av. Alberto Lamego, Campos dos Goytacazes, RJ, Brazil. Unidade de Biologia Integrativa, Setor de Genômica e Proteômica, UENF, Campos dos Goytacazes, RJ, Brazil. (4)
1Department of Biology, National and Kapodistrian University of Athens, Panepistimioupolis, Athens, 15784, Greece. 2Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, 70013, Greece. (2)
Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei 230022, China (2)
-Centre of Microbial and Plant Genetics; KU Leuven; Leuven, 3000; Belgium -Center for Microbiology; VIB-KU Leuven; Leuven, 3000; Belgium (1)
1 Centre of Microbial and Plant Genetics; KU Leuven; Leuven, 3000; Belgium 2 Center for Microbiology; VIB-KU Leuven; Leuven, 3000; Belgium (1)
1Research Unit Protein Science and Metabolomics and Proteomics Core, Helmholtz Zentrum München, German Research Center for Environmental Health, D-85764 Neuherberg, Germany (1)
Ascano Lab, Biochemistry Department, Vanderbilt University, Nashville TN, USA (1)
Australian National University, ACT, Australia (1)
CAncer Biology Lab, Instituto de Investigaciones Bioquímicas de Bahía Blanca (CONICET), Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur, Bahía Blanca, Argentina (1)
CNIC (1)
Center for Metabolic Disease Research (CMDR) Lewis Katz School of Medicine at Temple University Medical Education and Research Building, Room 1060 3500 N. Broad Street Philadelphia, PA 19140, USA (1)
Center for Regeneration and Aging,BGI-haangzhou (1)
Center of Excellence in Systems Biology, Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand (1)
Centre for Gene Regulation and Expression, School of Life Science, University of Dundee (1)
Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet SE 17177 Stockholm, Sweden. Department of Pharmacological & Technological Chemistry, I.M. Sechenov First Moscow State Medical University, Moscow, 119146, Russia. (1)
Clinical Chemistry, Department of Translational Medicine, Lund University, Skane University Hospital Malmö, 205 02 Malmö, Sweden. (1)
Copenhagen Center for Glycomics (CCG), Department of Cellular and Molecular Medicine, University of Copenhagen, Denmark (1)
Core Facility for Mass spectrometry & Proteomics, Max Planck Institut Marburg, Germany (1)
Dep. of Biology, University of Fribourg, Switzerland (1)
Departement of biochemistry and functional genomic, Sherbrooke university, Sherbrooke, Quebec, Canada (1)
Department of Biochemistry, Institute of Chemistry, University of São Paulo, 05508-000, São Paulo, SP, Brazil. (1)
Department of Biological Engineering, MIT, Cambridge, USA Ragon Institute of Mass General, Harvard, and MIT, Cambridge, USA (1)
Department of Biological Sciences, University of Bergen, Bergen, Norway (1)
Department of Biology, National and Kapodistrian University of Athens, Panepistimioupolis, Athens, 15784, Greece. Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, Heraklion, 70013, Greece. (1)
Department of Cell Biology, Harvard Medical School, Boston MA, USA (1)
Department of Chemistry, CICECO – Aveiro Institute of Materials, University of Aveiro Lab: COMPASS Research Group (1)
Department of Chemistry, University of California Riverside (1)
Department of Computational, Cellular, Integrative Biology (DeCIBIO), University of Trento 38123, TN, Italy (1)
Department of Hematology, University Hospital Leuven, Leuven, Belgium (1)
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17165, Sweden. (1)

IsPrivate

False (2)

Classification

viruses (1)
fungi (1)
bacteria (1)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (515)
RNA-seq of coding RNA (139)
ChIP-seq (55)
RNA-seq of non coding RNA (47)
RNA-seq of coding RNA from single cells (22)
Methylation profiling by array (15)
Other (12)
ChIP-chip by tiling array (10)
Unknown experiment type (6)
Cell line - High-throughput sequencing (6)
MicroRNA profiling by array (6)
RNA-seq of total RNA (6)
Methylation profiling by high throughput sequencing (5)
Transcription profiling by tiling array (4)
RNAi profiling by array (4)
ChIP-chip by array (4)
Transcription profiling by SAGE (3)
Comparative genomic hybridization by array (3)
Hi-C (3)
CUT&RUN (3)
Human - High-throughput sequencing (2)
Cell line - One-color microarray (2)
ATAC-seq (2)
DNA-seq (2)
Cell line - Single-cell sequencing (1)
Baseline (1)
RNA-seq of non coding RNA from single cells (1)
Human - Single-cell sequencing (1)
Plant - High-throughput sequencing (1)
High-throughput sequencing (1)

Release Date

2014 (148)
2015 (121)
2013 (112)
2012 (103)
2025 (100)
2016 (97)
2011 (89)
2010 (89)
2022 (86)
2021 (86)
2020 (77)
2024 (65)
2023 (59)
2019 (54)
2017 (52)
2018 (51)
2009 (42)
2008 (42)
2026 (33)
2007 (31)
2005 (8)
2006 (6)
2004 (6)
2002 (3)
1998 (2)
2003 (1)
2001 (1)
2000 (1)
1977 (1)

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Transcriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Uterine data)

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selec...

2024-05-30 | MTBLS9795 | MetaboLights

Transcriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Ovarian data)

2024-05-30 | MTBLS9794 | MetaboLights

Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease

Allergic diseases affect millions of people worldwide. An increase in their prevalence has been associated with alterations in the gut microbiome, i.e., the microorganisms and their genes within the gastrointestinal tract. Maturation of the infant immune system and gut microbiota occur in parallel; ...

2024-10-24 | MTBLS7919 | MetaboLights

Comprehensive multi-omics analysis reveals the influence of epigenetic mechanisms on porcine oocyte maturation

In vitro maturation (IVM) oocyte is a key component of assisted reproduction in pigs. Asynchronous nucleoplasmic maturation and incomplete cytoplasmic maturation is one of the key factors for impaired maturation and quality of oocytes matured in vitro. Although Single-omics techniques have been appl...

2025-08-27 | MTBLS12325 | MetaboLights

Advanced iPSC-CMs maturation by integrating maturation medium, nanopatterning, and electrical stimulation

The generation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) offers an unlimited source of patient-specific human cardiomyocytes. However, the use of iPSC-CM in vitro-models to guide the clinic selection of particular drugs for individual patients remains a vision. A major...

EGAS00001007491 | EGA

Proteome of human and mouse astrocytes and astrocyte-conditioned medium

ORGANISM(S): Homo Sapiens Mus Musculus

2025-02-05 | PXD060495 |

Advanced iPSC-CMs maturation by integrating maturation medium, nanopatterning, and electrical stimulation

PRJNA1227485 | ENA

SAGE in Cultured Murine COC During Early Maturation

In cultured cumulus oocyte complexes (COC) FSH induces gene transcription required for germinal vesicle breakdown (GVBD). Experiments were performed to determine the critical period when gene transcription is required for GVBD and identify candidate mRNAs involved. Experiment I: murine COC were cult...

ORGANISM(S): Mus musculus

2006-08-31 | E-GEOD-5568 | biostudies-arrayexpress

Downregulation of Myc is essential for terminal erythroid maturation

Terminal differentiation of mammalian erythroid progenitors involves 4-5 cell divisions and induction of many erythroid important genes, followed by chromatin and nuclear condensation and enucleation. The protein levels of c-myc (Myc) are reduced dramatically during late stage erythroid maturation, ...

ORGANISM(S): Mus musculus

2010-10-13 | E-GEOD-18558 | biostudies-arrayexpress

RNA Sequencing Analysis of Mouse Bone Marrow Derived Dendritic Cells Transcriptomes During Maturation

Purpose:The purpose of this study is to detect activated or silenced genes during LPS-induced dendritic cell maturation. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis. Methods:Mouse dendritic cells were generated from bone marrow cell...

ORGANISM(S): Mus musculus

2015-03-04 | E-GEOD-60307 | biostudies-arrayexpress

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