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TranscriptomicsDifferential effects of TNFalpha and IL1beta on FLS global gene expression profile
TNFalpha and IL1beta play a pathogenic role in rheumatoid arthritis. Both cytokines are known to activate cytokine and metalloproteinase secretion by synovial fibroblasts. In the present study, we wanted to investigate whether TNFalpha and IL1beta displayed differential effects on cultured Fibroblas...
ORGANISM(S): Homo sapiens 
2009-04-15 | E-GEOD-15615 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in RA synovial biopsies from responders versus non-responders to adalimumab therapy
TNF antagonists are routinely used in severe rheumatoid arthritis (RA) patients who failed conventional DMARD therapy. According to large clinical trials, the three available drugs (adalimumab, infliximab and etanercept) display similar effects in terms of efficacy, tolerability and side effects. Th...
ORGANISM(S): Homo sapiens 
2009-04-15 | E-GEOD-15602 | biostudies-arrayexpress
UnknownIndustrial chicory genome gives insights into the molecular timetable of anther development and male sterility.
Not available
S-EPMC10298185 | biostudies-literature
UnknownVestibular Deficits in Deafness: Clinical Presentation, Animal Modeling, and Treatment Solutions.
Not available
S-EPMC9013928 | biostudies-literature
UnknownAdvancing precision ear medicine: leveraging animal models for disease insights and therapeutic innovations.
Not available
S-EPMC12130096 | biostudies-literature
UnknownGene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis.
Not available
S-EPMC2688209 | biostudies-literature
UnknownTinnitus and distress: an electroencephalography classification study.
Not available
S-EPMC9927883 | biostudies-literature
UnknownOlfactory function in congenital cytomegalovirus infection: a prospective study.
Not available
S-EPMC8758467 | biostudies-literature
UnknownCognitive function and sleep related breathing disorders in a healthy elderly population: the SYNAPSE study.
Not available
S-EPMC2849791 | biostudies-literature
UnknownClarin-2 gene supplementation durably preserves hearing in a model of progressive hearing loss.
Not available
S-EPMC10928142 | biostudies-literature
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