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GenomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-Seq
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20530 | biostudies-arrayexpress
TranscriptomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-chip
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20529 | biostudies-arrayexpress
Transcriptomics5' Cap-Isolated RNA Pol II Transcripts and ENCODE Tiling Arrays to Identify Gene Expression Changes in Hepatitis C Liver
Recent studies of the human transcriptome suggest that many transcripts have short or lack 3' poly(A) ends. In addition, the length of 3' poly(A) ends may vary for some transcript to regulate mRNA translation. Heterogeneous lengths of poly(A) ends may introduce variations in measuring RNA transcript...
ORGANISM(S): Homo sapiens 
2011-03-29 | E-GEOD-18904 | biostudies-arrayexpress
OtherWidespread Proteome Remodeling and Aggregation in Aging C. elegans.
Data from ProteomeXchange, PXD ID: PXD001364. Experiment: AggregatesSILAC_DAF16_D01, file: 20110921_Velos3_DiWa_SA_Celegans_AggregatesSILAC_DAF16_D01-3.mzml. Published as part of Cell. 2015 May 7;161(4):919-932 . From the Abstract: {{i}} ... Here, we profiled more than 5, 000 proteins along the lif...
ORGANISM(S): Worm, Escherichia_coli_k_12_substr__mg1655 
GPM32310019629 | GPMDB
Resource Reanalysis 
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - nuclear proteins of elderly B cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000082941 | MassIVE
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - nuclear proteins of CLL cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo sapiens (Human) 
2017-12-06 | PXD006589 | Pride
Glutaminolysis Chronic lymphocytic leukemia Shotgun proteomics Primary human b lymphocytes Aging Fatty acid beta oxidation Q exactive orbitrap 
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - cytoplasmic proteins of CLL cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo sapiens (Human) 
2017-12-06 | PXD006578 | Pride
Glutaminolysis Chronic lymphocytic leukemia Shotgun proteomics Primary human b lymphocytes Aging Fatty acid beta oxidation Q exactive orbitrap 
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - nuclear proteins of JVM-13 cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo sapiens (Human) 
2017-12-06 | PXD006590 | Pride
Glutaminolysis Chronic lymphocytic leukemia Shotgun proteomics Primary human b lymphocytes Aging Fatty acid beta oxidation Q exactive orbitrap 
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - nuclear proteins of young B cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo sapiens (Human) 
2017-12-05 | PXD006576 | Pride
Glutaminolysis Chronic lymphocytic leukemia Shotgun proteomics Primary human b lymphocytes Aging Fatty acid beta oxidation Q exactive orbitrap 
ProteomicsAging-related proteome alterations in B cells may predispose for chronic lymphocytic leukemia - nuclear proteins of elderly B cells
Chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults, is still incurable despite the development of novel therapeutic strategies. This reflects the incomplete understanding of the pathophysiology of this disease. In order to get more detailed insights into CLL development, ...
ORGANISM(S): Homo sapiens (Human) 
2017-12-05 | PXD006571 | Pride
Glutaminolysis Chronic lymphocytic leukemia Shotgun proteomics Primary human b lymphocytes Aging Fatty acid beta oxidation Q exactive orbitrap 
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