Sort   by:  
 Page size 
TranscriptomicsA single therapeutic early-in-life antibiotic course alters host immunologic development
Broad-spectrum antibiotics are frequently prescribed to children. The period of early-childhood represents a time where the developing microbiota may be more sensitive to environmental perturbations, which thus might have long-lasting host consequences. We hypothesized that even a single early-life ...
ORGANISM(S): Mus musculus 
2017-09-19 | E-MTAB-5101 | biostudies-arrayexpress
ProteomicsPathology tissue-quantitative mass spectrometry analysis to profile histone post-translational modification patterns in patient samples
Histone post-translational modifications (hPTMs) generate a complex combinatorial code that has been implicated with various pathologies, including cancer. Dissecting such a code in physiological and diseased states may be exploited for epigenetic biomarker discovery, but hPTM analysis in clinical s...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2016-08-25 | MSV000080100 | MassIVE
TranscriptomicsThe effect of a single or multiple pulsed antibiotic exposure in C57BL/6 mice
Broad-spectrum antibiotics are frequently prescribed to children. The period of early-childhood represents a time where the developing microbiota may be more sensitive to environmental perturbations, which thus might have long-lasting host consequences. We hypothesized that even a single early-life ...
ORGANISM(S): Mus musculus 
2017-09-18 | GSE98022 | GEO
GenomicsA single therapeutic early-in-life antibiotic course alters host immunologic development
A single therapeutic early-in-life antibiotic course alters host immunologic development
PRJEB15433 | ENA
TranscriptomicsThe effect of early life antibiotic treatment in germ-free or SPF colonized C57BL/6 mice
Broad-spectrum antibiotics are frequently prescribed to children. The period of early-childhood represents a time where the developing microbiota may be more sensitive to environmental perturbations, which thus might have long-lasting host consequences. We hypothesized that even a single early-life ...
ORGANISM(S): Mus musculus 
2017-09-18 | GSE98291 | GEO
TranscriptomicsMetabolic and metagenomic outcomes from early-life pulsed antibiotic treatment
Mammalian species have co-evolved with intestinal microbial communities that can shape development and adapt to environmental changes, including antibiotic perturbation or nutrient flux. In humans, especially children, microbiota disruption is common, yet the dynamic microbiome recovery from early-...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-68603 | biostudies-arrayexpress
GenomicsMus musculus
The effect of a single or multiple pulsed antibiotic exposure in C57BL/6 mice
PRJNA383708 | ENA
TranscriptomicsGene transcriptional levels with or without acid treatment in Salmonella Typhimurium 14028s
Acetylation of lysine residues is conserved across organisms and plays important roles in various cellular functions. Maintaining intracellular pH homeostasis is crucial for the survival of enteric bacteria in acidic gastric tract. However, it remains unkown whether bacteria can utilize reversible p...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 
2015-04-16 | E-GEOD-67925 | biostudies-arrayexpress
TranscriptomicsMetabolic and metagenomic outcomes from early-life pulsed antibiotic treatment
Mammalian species have co-evolved with intestinal microbial communities that can shape development and adapt to environmental changes, including antibiotic perturbation or nutrient flux. In humans, especially children, microbiota disruption is common, yet the dynamic microbiome recovery from early-l...
ORGANISM(S): Mus musculus 
2015-05-07 | GSE68603 | GEO
UnknownPerformance Metrics of the Scoring System for the Diagnosis of the Beckwith-Wiedemann Spectrum (BWSp) and Its Correlation with Cancer Development.
Not available
S-EPMC9913441 | biostudies-literature
Sort   by:  
 Page size