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ProteomicsPredictive protein biomarker signatures and the corresponding transcriptional cell state changes in human lung fibrosis (Plasma)
Single cell genomics enables characterization of disease specific cell states, while improvements in mass spectrometry workflows bring the clinical use of body fluid proteomics within reach. However, the correspondence of peripheral protein signatures to changes in cell state in diseased organs is c...
ORGANISM(S): Homo sapiens (Human) 
2020-09-18 | PXD017210 | Pride
Data integration Proteomics Fibrosis Single cell rna-seq Systems medicine Biomarker 
MetabolomicsPhospholipid acyl chain diversity controls the tissue-specific assembly of mitochondrial cardiolipins

Cardiolipin (CL) is a phospholipid specific for mitochondrial membranes and crucial for many core tasks of this organelle. Its side chain configurations are tissue-specific, functionally important and generated via post-biosynthetic remodeling. However, this process lacks the necessary specificit...

2020-05-22 | MTBLS1446 | MetaboLights
ProteomicsPredictive protein biomarker signatures and the corresponding transcriptional cell state changes in human lung fibrosis
Single cell genomics enables characterization of disease specific cell states, while improvements in mass spectrometry workflows bring the clinical use of body fluid proteomics within sight. However, the correspondence of peripheral protein signatures with cell state changes in diseased organs is cu...
ORGANISM(S): Homo sapiens (Human) 
2020-09-18 | PXD017145 | Pride
Data integration Proteomics Fibrosis Single cell rna-seq Systems medicine Biomarker 
TranscriptomicsTranscription profiling of mouse primary capillary PlGF-/- endothelial cells treated with 100 ng/ml PlGF for 6 hours
PlGF expression profile in primary capillary PlGF-/- endothelial cells treated with 100 ng/ml PlGF during 6 hours.
ORGANISM(S): Mus musculus 
2003-05-28 | E-MEXP-6 | biostudies-arrayexpress
ProteomicsM.musculus - Lung, iBAQ (Angelidisetal,natcommun.2019)
abundance based on iBAQ, Interaction consistency score: 8.7, Coverage: 21
ORGANISM(S): 10090 
2019-00-00 | 386924191 | PAXDB
ProteomicsM.musculus - Lung, iBAQ (Angelidisetal,natcommun.2019)
abundance based on iBAQ, Interaction consistency score: 9.7, Coverage: 21
ORGANISM(S): 10090 
2019-00-00 | 3284560666 | PAXDB
UnknownIntegrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers
Not available
S-SCDT-EMM-2020-12871 | biostudies-other
UnknownThe effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Not available
S-EPMC3145073 | biostudies-literature
UnknownEffect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
Not available
S-EPMC8491132 | biostudies-literature
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