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mRNA expression data in FACS sorted CD11b+ F4/80+ tumor-associated macrophages that are derived from normoxic (as characterized by low GLUT1-expression on the cell membrane) or hypoxic (as characterized by high GLUT1-expression on the cell membrane) area's of Lewis Lung Carcinoma tumors injected sub...
ORGANISM(S): Mus musculus 
In this study, we discover an essential role for the mitochondrial glutamate-aspartate antiporter SLC25A13 in biomass synthesis in endothelial cells (ECs). To delineate the global changes of SLC25A13 silencing at a molecular level, we performed high-throughput bulk RNA-sequencing and analyzed the di...
ORGANISM(S): Homo sapiens 
PLCG1 R707Q mutation is counter selected under targeted therapy in a patient with a hepatic angiosarcoma
Data Access Committee EGAC00001000042
Analysis of tumor-educated changes in peripheral blood monocytes at the gene expression level. We analyzed if gene expression in monocytes of patients with colorectal cancer is differential from those of healthy volunteers and found a diagnostic signature that allowed to accurately discriminate pati...
ORGANISM(S): Homo sapiens 
Attention to exploring endothelial cell (EC) metabolism is increasing, but a holistic perspective on the metabolic adaptations of ECs during angiogenic proliferation, is still missing. Here, we use a previously in-house developed computational EC-adapted genome scale metabolic model that recapitulat...
2026-08-10 | MTBLS15306 | MetaboLights
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