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Deconvolution analysis using Rpb1 ChIP-chip results distinguishes the Cdc10 bindings at the Rpb1-poor loci (promoters) from those at the Rpb1-rich loci (intragenic sequences). Importantly, Res1 binding at the Rpb1-poor loci, but not at the Rpb1-rich loci, are dependent on the Cdc10 function, suggest...
ORGANISM(S): Schizosaccharomyces pombe 
MBF and SBF transcription factors regulate a large family of coordinately expressed G1/S genes required for early cell cycle functions including DNA replication and repair. SBF is inactivated upon S phase entry by Clb/CDK whereas MBF targets are repressed by the corepressor, Nrm1. Using genome-wide ...
ORGANISM(S): Saccharomyces cerevisiae 
Fission yeast Whi5 represses MBF-dependent transcription in quiescent cells
Fission yeast Whi5 represses MBF-dependent transcription in quiescent cells II
Transcription profiling of fission yeast /yox1/ deletion and genome wide location analysis of Yox1p and Cdc10p transcription factors reveal a negative feedback interaction: /yox1 /is transcriptionally activated by MBF, and Yox1p in turn transcriptionally represses the MBF target genes (including /yo...
ORGANISM(S): Schizosaccharomyces pombe 
Transcription profiling of fission yeast /yox1/ deletion and genome wide location analysis of Yox1p and Cdc10p transcription factors reveal a negative feedback interaction: /yox1 /is transcriptionally activated by MBF, and Yox1p in turn transcriptionally represses the MBF target genes (including /yo...
ORGANISM(S): Schizosaccharomyces pombe 
When cells arrest the cell cycle in G1 to enter the non-dividing quiescent state, the transcriptional machinery that promotes G1/S transition must be inactivated. Central to this regulation is Whi5, in budding yeast, and the Retinoblastoma (Rb) protein, in mammalian cells, acting as repressors of th...
ORGANISM(S): Schizosaccharomyces pombe 
2025-12-20 | GSE285081 | GEO
When cells arrest the cell cycle in G1 to enter the non-dividing quiescent state, the transcriptional machinery that promotes G1/S transition must be inactivated. Central to this regulation is Whi5, in budding yeast, and the Retinoblastoma (Rb) protein, in mammalian cells, acting as repressors of th...
ORGANISM(S): Schizosaccharomyces pombe 
2025-12-20 | GSE285763 | GEO
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