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UnknownNative IM-Orbitrap MS: Resolving What Was Hidden.
Not available
S-EPMC7079669 | biostudies-literature
UnknownMolecular Mechanism of ISC Iron-Sulfur Cluster Biogenesis Revealed by High-Resolution Native Mass Spectrometry.
Not available
S-EPMC7262672 | biostudies-literature
UnknownTHE IMS PARADOX: A PERSPECTIVE ON STRUCTURAL ION MOBILITY-MASS SPECTROMETRY.
Not available
S-EPMC7989064 | biostudies-literature
TranscriptomicsTranscriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology
Background: Weaning of beef calves is a necessary husbandry practice and involves separating the calf from its mother, resulting in numerous stressful events including dietary change, social reorganisation and the cessation of the maternal-offspring bond and is often accompanied by housing. While mu...
ORGANISM(S): Bos taurus 
2012-06-25 | E-GEOD-37447 | biostudies-arrayexpress
UnknownDown syndrome: national conference on patient registries, research databases, and biobanks.
Not available
S-EPMC3171614 | biostudies-literature
MetabolomicsER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis
The unfolded protein response (UPR), induced by endoplasmic reticulum (ER) stress, regulates the expression of factors that restore protein folding homeostasis. However, in the liver and kidney, ER stress also leads to lipid accumulation, accompanied at least in the liver by transcriptional suppress...
2017-06-23 | MTBLS472 | MetaboLights
ProteomicsInfluence of generational obesity on the visceral adipose proteome
Obesity is a global health concern affecting over 650 million adults with a major contributor being an increased consumption of a high-fat diet. Maternal obesity often results in an increased risk of offspring developing obesity. In this study, we examined the effect of diet on visceral adipose in ...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD042092 | Pride
Proteomics Suspension trapping Generational obesity Omental tissue Adipose tissue Mouse Diet S-trap 
ProteomicsDrug Screening in 3D Microtumors Reveals DDR1/2-MAPK12-GLI1 as a Vulnerability in Cancer-Associated Fibroblasts
Interactions between cancer cells and surrounding stromal cells are critical for tumor biology and treatment response. We compare drug screening results from conventional 2D cancer cell lines with 3D tumor tissues and find that, on average, three times more drugs are effective in 3D microtumors. We ...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-15 | PXD066684 | Pride
Drug screening Cancer Fibroblasts Doramapimod Extracellular matrix 
UnknownDivergent functional isoforms drive niche specialisation for nutrient acquisition and use in rumen microbiome.
Not available
S-EPMC5364355 | biostudies-literature
ProteomicsProteomic signatures of radioresistance: Alteration of inflammation, angiogenesis and metabolism-related factors in radioresistant oesophageal adenocarcinomav
The clinical management of locally advanced oesophageal adenocarcinoma (OAC) commonly involves neoadjuvant chemoradiotherapy (CRT), but complete pathological response to CRT only occurs in 20-30% of patients, as radioresistance remains a major clinical challenge. In this study we used an established...
ORGANISM(S): Homo sapiens (Human) 
2022-08-18 | PXD020303 | Pride
Oesophageal adenocarcinoma Oac 
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