Sort   by:  
 Page size 
TranscriptomicsmiRNA-sequencing of human pancreatic islets and enriched beta-cells
Recent advances in the understanding of the genetics of type 2 diabetes (T2D) susceptibility have focused attention on the regulation of transcriptional activity within the pancreatic beta-cell. MicroRNAs (miRNAs) represent an important component of regulatory control, and have proven roles in the d...
ORGANISM(S): Homo sapiens 
2013-06-07 | E-GEOD-47720 | biostudies-arrayexpress
TranscriptomicsVariability of gene expression profiles in human blood and lymphoblastoid cell lines
Readily accessible samples such as peripheral blood or cell lines are increasingly being used in large cohorts to characterise gene expression differences between a patient group and healthy controls. However, cell and RNA isolation procedures and the variety of cell types that make up whole blood c...
ORGANISM(S): Homo sapiens 
2011-07-25 | E-GEOD-30916 | biostudies-arrayexpress
TranscriptomicsMiRNA expression in adipose tissue and liver from a spontaneous rat model of Type 2 diabetes
MicroRNAs (miRNAs) are non-coding RNA molecules involved in post-transcriptional control of gene expression of a wide number of genes, including those involved in glucose homeostasis. Type 2 diabetes (T2D) is characterized by hyperglycaemia and defects in insulin secretion and action at target tissu...
ORGANISM(S): Rattus norvegicus 
2010-05-16 | E-GEOD-17058 | biostudies-arrayexpress
GenomicsPopulation whole-genome bisulfite sequencing across two tissues highlights environment as principal source of human methylome variation
The study includes whole-genome bisulfite sequencing (WGBS) on 34 adipose (7 MZ pairs, 6 DZ pairs and 8 singletons) and 27 blood (7 MZ pairs, 6 DZ pairs and 1 singleton) DNA samples derived from a total of 43 female twins belonging to the MuTHER/TwinsUK cohort. We generated 11.5 billion 100bp paired...
EGAS00001001569 | EGA
Genomicsena-DATASET-MCGILL-25-11-2015-16:17:41:115-10 - samples
Description not provided
EGAD00001001689 | EGA
Genomicsena-DATASET-MCGILL-25-11-2015-16:14:18:542-9 - samples
Description not provided
EGAD00001001688 | EGA
GenomicsMcGill-KCL WGBS
Data Access Committee EGAC00001000402
EGAC00001000402 | EGA
Genomicsena-DATASET-OCDEM-04-09-2015-16:46:25:090-47 - samples
The intersection of genome-wide association analyses with physiological and functional data indicates that variants regulating islet gene transcription influence type 2 diabetes (T2D) predisposition and glucose homeostasis. However, the specific genes through which these regulatory variants act rema...
EGAD00001001601 | EGA
Genomicscis-eQTL mapping of human pancreatic islets
The intersection of genome-wide association analyses with physiological and functional data indicates that variants regulating islet gene transcription influence type 2 diabetes predisposition and glucose homeostasis. However, the specific genes through which these regulatory variants act remain po...
EGAS00001001265 | EGA
GenomicsOxford Human Islet Data Access Committee
Data Access Committee EGAC00001000335
EGAC00001000335 | EGA
Sort   by:  
 Page size