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GenomicsLarge-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [ChIP-Seq]
During pancreatic cancer progression, heterogeneous subclonal populations evolve in the primary tumor that possess differing capacities to metastasize and cause patient death. However, the genetics of metastasis reflects that of the primary tumor, and PDAC driver mutations arise early. This raises t...
ORGANISM(S): Homo sapiens 
2016-10-24 | E-GEOD-63125 | biostudies-arrayexpress
TranscriptomicsLarge-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [RNA-Seq]
During pancreatic cancer progression, heterogeneous subclonal populations evolve in the primary tumor that possess differing capacities to metastasize and cause patient death. However, the genetics of metastasis reflects that of the primary tumor, and PDAC driver mutations arise early. This raises t...
ORGANISM(S): Homo sapiens 
2016-10-24 | E-GEOD-63124 | biostudies-arrayexpress
Genomicsena-DATASET-RTL-03-05-2017-12:40:06:735-476 - samples
RNAseq of LC2AD with AD80 or DMSO Plenker et al., Mechanistic insight into RET kinase inhibitors targeting the DFG-out conformation in RET-rearranged cancer
EGAD00001003316 | EGA
UnknownIntegrin beta-like 1 is regulated by DNA methylation and increased in heart failure patients.
Not available
S-EPMC11769624 | biostudies-literature
GenomicsDrugging the catalytically inactive state of RET kinase in RET-rearranged tumors.
Oncogenic fusion events have been identified in a broad range of tumors. Among them, RET rearrangements represent distinct and potentially druggable targets that are recurrently found in lung adenocarcinomas. We provide further evidence that current anti-RET drugs may not be potent enough to induce ...
EGAS00001002335 | EGA
UnknownEvaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States.
Not available
S-EPMC9169655 | biostudies-literature
UnknownOutpatient hospital attendances in people with rheumatoid arthritis during the COVID-19 pandemic and beyond: a cohort study in three nations of the UK.
Not available
S-EPMC12862379 | biostudies-literature
TranscriptomicsTranscription profiling by array of Candida albicans populations exposed to a temperature shift from 25 degrees to 37 degrees
Seperate White and Opaque Candida albicans populations were exposed to a temperature shift from 25 degrees to 37 degrees. Samples were then harvested at various time points to follow the effects of the shift on the two cell types, particularly the opaque cell type which switches to the white cell ...
ORGANISM(S): Candida albicans 
2011-05-08 | E-MEXP-2705 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of C. albicans to identify the commintment point of the temperature induced opaque-to-white switch
This experiment is a characterization of the commitment point of the temperature induced opaque-to-white switch in the fungal pathogen Candida albicans. This experiment examines changes in the transcriptome occurring at the 50% commitment points for both the wild type and WOR1/wor1 strains in order...
ORGANISM(S): Candida albicans 
2011-07-07 | E-MEXP-2834 | biostudies-arrayexpress
UnknownPSYSCAN multi-centre study: baseline characteristics and clinical outcomes of the clinical high risk for psychosis sample.
Not available
S-EPMC12006469 | biostudies-literature
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