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UnknownText-mining clinically relevant cancer biomarkers for curation into the CIViC database.
Not available
S-EPMC6891984 | biostudies-literature
UnknownStandard operating procedure for curation and clinical interpretation of variants in cancer.
Not available
S-EPMC6883603 | biostudies-literature
UnknownA multiple myeloma-specific capture sequencing platform discovers novel translocations and frequent, risk-associated point mutations in IGLL5.
Not available
S-EPMC5862875 | biostudies-literature
UnknownCIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer.
Not available
S-EPMC5367263 | biostudies-literature
TranscriptomicsConvergence of oncogenic and hormone receptor pathways promotes pro-metastatic phenotypes.
Cyclin D1b is a splice variant of the cell cycle regulator Cyclin D1 and is known to harbor divergent and highly oncogenic functions in human disease. While Cyclin D1b is induced during disease progression in many cancer types, the mechanisms underlying Cyclin D1b function remain poorly understood. ...
ORGANISM(S): Homo sapiens 
2013-03-31 | E-GEOD-40794 | biostudies-arrayexpress
UnknownSirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice.
Not available
S-EPMC12059161 | biostudies-literature
UnknownDNA defects, epigenetics, and gene expression in cancer-adjacent breast: a study from The Cancer Genome Atlas.
Not available
S-EPMC5515343 | biostudies-literature
UnknownA community approach to the cancer-variant-interpretation bottleneck.
Not available
S-EPMC9872366 | biostudies-literature
TranscriptomicsEffects of ONC201 on mantle cell lymphoma cell lines
The small molecule ONC201 is toxic in vitro to multiple cell lines and primary tumor samples of mantle cell lymphoma (MCL) and acute myeloid leukemia, even ones with unfavorable genetic features (notably including TP53 inactivation) or acquired resistance to other agents. Because the mechanism of ac...
ORGANISM(S): Homo sapiens 
2016-02-20 | E-GEOD-68091 | biostudies-arrayexpress
UnknownPhenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.
Not available
S-EPMC5771958 | biostudies-literature
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