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UnknownDescribing Multidomain Health Outcomes in Autistic Children in the ECHO Program.

Objective

The goal of this study is to characterize health outcomes across 3 domains-overall well-being, behavioral health, and physical health-in a large sample of autistic and non-autistic children and adolescents in the Environmental influences on Child Health Outcomes (ECHO) program.

...

S-EPMC12414301 | biostudies-literature
UnknownPrenatal exposure to organophosphate ester flame retardants and behavioral outcomes in early childhood in the Environmental influences on Child Health Outcomes (ECHO) cohort.

Background

Prenatal exposure to organophosphate esters (OPEs) has been linked to neurotoxic effects in children; however, epidemiological evidence remains inconclusive. We investigated associations of prenatal OPE exposure with child behaviors.

Methods

We analyzed data of 2948 mother-...
S-EPMC12498345 | biostudies-literature
UnknownCOVID-19 Stress and Child Behavior: Examining Discrimination and Social Support in Racially Diverse ECHO Cohorts.

Objective

To examine the additive or moderating influences of caregiver COVID-19-related stress, social support, and discrimination on children's behavior problems across racially diverse populations.

Method

In this Environmental influences on Child Health Outcomes (ECHO) cohort study...
S-EPMC10838355 | biostudies-literature
UnknownBirth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort study.

Background

Limited access to healthy foods, resulting from residence in neighborhoods with low-food access or from household food insecurity, is a public health concern. Contributions of these measures during pregnancy to birth outcomes remain understudied.

Objectives

We examined asso...
S-EPMC11130689 | biostudies-literature
UnknownEvaluation of pediatric epigenetic clocks across multiple tissues.

Background

Epigenetic clocks are promising tools for assessing biological age. We assessed the accuracy of pediatric epigenetic clocks in gestational and chronological age determination.

Results

Our study used data from seven tissue types on three DNA methylation profiling microarrays...
S-EPMC10475199 | biostudies-literature
UnknownSociodemographic Differences in COVID-19 Pandemic Experiences Among Families in the United States.

Importance

Few population-based studies in the US collected individual-level data from families during the COVID-19 pandemic.

Objective

To examine differences in COVID-19 pandemic-related experiences in a large sociodemographically diverse sample of children and caregivers.

Design,...

S-EPMC10448300 | biostudies-literature
UnknownNeighborhood Food Access in Early Life and Trajectories of Child Body Mass Index and Obesity.

Importance

Limited access to healthy foods, resulting from residence in neighborhoods with low food access, is a public health concern. The contribution of this exposure in early life to child obesity remains uncertain.

Objective

To examine associations of neighborhood food access dur...
S-EPMC11406455 | biostudies-literature
UnknownTherapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19.

Background

Thrombosis and inflammation may contribute to morbidity and mortality among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation would improve outcomes in critically ill patients with Covid-19.

Methods

In an open-label, ad...
S-EPMC8362592 | biostudies-literature
UnknownHost factors are associated with vaginal microbiome structure in pregnancy in the ECHO Cohort Consortium.
Using pooled vaginal microbiota data from pregnancy cohorts (N = 683 participants) in the Environmental influences on Child Health Outcomes (ECHO) Program, we analyzed 16S rRNA gene amplicon sequences to identify clinical and demographic host factors that associate with vaginal microbiota structure ...
S-EPMC11116393 | biostudies-literature
UnknownThe Association of Prenatal Dietary Factors with Child Autism Diagnosis and Autism-Related Traits Using a Mixtures Approach: Results from the Environmental Influences on Child Health Outcomes Cohort.

Background

Previous research on the role of maternal diet in relation to autism has focused on examining individual nutrient associations. Few studies have examined associations with multiple nutrients using mixtures approaches, which may better reflect true exposure scenarios.

Objectives...

S-EPMC12264552 | biostudies-literature
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