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TranscriptomicsTranscription profiling of S. cerevisiae cultures grown under low shear-modeled microgravity
The goal of this study was to assess whether low shear-modeled microgravity (LSMMG) effects yeast ,genomic expression patterns using the powerful tool of whole genome microarray hybridization. We determined ,changes in the yeast model organism, Saccharomyces cerevisisae, when grown in LSMMG using th...
ORGANISM(S): Saccharomyces cerevisiae 
2007-07-07 | E-GEOD-4136 | biostudies-arrayexpress
TranscriptomicsType I IFN-signaling following Pneumocystis (PC)-infection and clearance in CD4 T cell-competent mice
Type I IFN-signaling suppresses an excessive IFN-{gamma} response and prevents lung damage and chronic inflammation following Pneumocystis (PC)-infection and clearance in CD4 T cell-competent mice. Type I IFN -signaling in pulmonary CD11c+ DCs and alveolar macrophages may prevent chronic inflammatio...
ORGANISM(S): Mus musculus 
2010-07-07 | E-GEOD-18607 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Xenopus laevis ectodermal explants following activation of hormone-inducible zic1
The response of ectodermal explants, neuralized by noggin and treated with cycloheximide, following activation of hormone-inducible zic1 injected into the parent embryos compared to those from beta globin injected embryos as controls, is expected to provide information on the direct targets of the Z...
ORGANISM(S): Xenopus laevis 
2009-07-10 | E-GEOD-12128 | biostudies-arrayexpress
TranscriptomicsPseudomonas aeruginosa biofilm cells contain ribosome hibernation factors in the dormant antibiotic-tolerant subpopulation
Bacteria growing in biofilms are physiologically heterogeneous, due in part to their adaptation to local environmental conditions. Here, we characterized the local transcriptional responses of Pseudomonas aeruginosa growing in biofilms by using microarray analysis of isolated biofilm subpopulations....
ORGANISM(S): Pseudomonas aeruginosa 
2012-05-02 | E-GEOD-34762 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of infection of the archaeon Sulfolobus solfataricus with STIV
Time series of infection of Sulfolobus solfataricus strain 2-2-12 cells infected with STIV are compared with uninfected cells over 32 h. Two-condition experiment, Control vs. Infected cells sampled at 5 time points (0, 8, 16, 24, 32 h post infection). Biological replicates: 3 control, 3 infected, pa...
ORGANISM(S): Sulfolobus solfataricus 
2008-07-25 | E-GEOD-12235 | biostudies-arrayexpress
TranscriptomicsAnalysis of Pseudomonas aeruginosa evolving in the cystic fibrosis lung uncovers limited evidence that mutator lineages are more genetically variable than non-mutator lineages
Pseudomonas aeruginosa evolving in the cystic fibrosis (CF) lung encounters selection via iron-limitation, antibiotics, immune system effectors and other microbes. Standing genetic variation, which depends on rates of horizontal gene transfer (HGT) and mutation supply, controls response to challenge...
ORGANISM(S): Pseudomonas aeruginosa 
2011-10-31 | E-GEOD-25481 | biostudies-arrayexpress
TranscriptomicsPhevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression
Staphylococcus aureus produces the cyclic dipeptides tyrvalin and phevalin (aureusimine A and B, respectively). A previous study reported that S. aureus mutants not capable of producing these compounds were less virulent in vivo through the deranged regulation of virulence factor genes. These findin...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-32920 | biostudies-arrayexpress
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