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ProteomicsExpression of Siglec-E alters the proteome of LPS-activated macrophages but does not affect LPS-driven cytokine production or TLR4 endocytosis Expression of Siglec-E alters the proteome of LPS-activated macrophages but does not affect LPS-driven cytokine production or TLR4 endocytosis
Siglec-E is a murine CD33-related siglec that functions as an inhibitory receptor and is expressed mainly on neutrophils and macrophage populations. Recent studies have suggested that siglec-E is an important negative regulator of LPS-TLR4 signalling and one report (Wu et al 2016) claimed that sigl...
ORGANISM(S): Mus musculus (Mouse) 
2018-02-09 | PXD008406 | Pride
Mouse bmdm lc-msms 
UnknownThe relationship between members of the canonical NF-κB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer.
Not available
S-EPMC5464845 | biostudies-literature
UnknownHistological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer.
Not available
S-EPMC7578335 | biostudies-literature
UnknownGermline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination.
Not available
S-EPMC8505423 | biostudies-literature
UnknownAddition of four doses of rituximab to standard induction chemotherapy in adult patients with precursor B-cell acute lymphoblastic leukaemia (UKALL14): a phase 3, multicentre, randomised controlled trial.
Not available
S-EPMC8969057 | biostudies-literature
MetabolomicsA female gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite
ATP-binding cassette (ABC) transporters serve a variety of physiological functions as well as play key roles in drug resistance. The genome of the human malaria parasite, Plasmodium falciparum, encodes multiple members of this family, one of which, gABCG2, is transcribed predominantly in the gametoc...
2016-09-14 | MTBLS98 | MetaboLights
UnknownIn-vivo T-cell depleted reduced-intensity conditioned allogeneic haematopoietic stem-cell transplantation for patients with acute lymphoblastic leukaemia in first remission: results from the prospective, single-arm evaluation of the UKALL14 trial.
Not available
S-EPMC8969058 | biostudies-literature
UnknownTreatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial.
Not available
S-EPMC7597675 | biostudies-literature
UnknownFunctional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness.
Not available
S-EPMC7895946 | biostudies-literature
UnknownMachine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis.
Not available
S-EPMC7799365 | biostudies-literature
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