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Fundamental alterations in lipid metabolism including increased rates of de novo lipogenesis (DNL), reduced fatty acid oxidation (FAOX) and ectopic lipid accumulation in skeletal muscle and liver are characteristic of type 2 diabetes mellitus (T2DM) and have been hypothesized to directly contribute ...
ORGANISM(S): Rattus norvegicus 
Germline mutation of BRCA2 increases the lifetime risk of developing prostate cancer (PCa) by over 700%. BRCA2-mutant PCa have poorer prognosis than sporadic PCa, with rapid development of metastatic, castrate-resistant prostate cancer (mCRPC) and 5-year cancer-specific survival rates of ~50-60%1-4....
single nucleotide variant calls from somatic sniper, vcf format. input for subclonal reconstruction
Aligned sequence data from 14 Prostate cancer samples with BRCA2 mutations
Raw Array data from the CPCGene BRCA study
single nucleotide variant calls from somatic sniper, vcf format
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