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GenomicsGenome-wide maps of nucleosome occupancy in human lymphoblastoid cell lines
Nucleosomes are important for gene regulation because their arrangement on the genome can control which proteins bind to DNA. Currently, few human nucleosomes are thought to be consistently positioned across cells; however, this has been difficult to assess due to the limited resolution of existing ...
ORGANISM(S): Homo sapiens 
2012-08-01 | E-GEOD-36979 | biostudies-arrayexpress
GenomicsIdentification of genetic variants that affect histone modifications in human cells
Histone modifications are important markers of function and chromatin state, yet the DNA elements that direct them to specific locations in the genome are poorly understood. Here we use the genetic variation in Yoruba lymphoblastoid cell lines as a natural experiment to identify genetic differences ...
ORGANISM(S): Homo sapiens 
2013-10-01 | E-GEOD-47991 | biostudies-arrayexpress
GenomicImpact of Genetic Polymorphisms on Human Immune Cell Gene Expression

While many genetic variants have been associated with risk for human diseases, how these variants affect gene expression in various cell types remains largely unknown. To address this gap, the DICE (Database of Immune Cell Expression, Expression quantitative trait loci (eQTLs) and Epigenomics) pr...

phs001703 | dbGaP
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