Mcl - OmicsDI

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Unknown (2812)
Transcriptomics (736)
Genomics (387)
Proteomics (72)
Other (16)
Methylation profiling (4)
Genomic (2)
Metabolomics (2)
Clinical (1)

Organisms

Homo sapiens (527)
Mus musculus (205)
Rattus norvegicus (39)
Zea mays (8)
Ovis aries (5)
Drosophila melanogaster (5)
Arabidopsis thaliana (5)
Oryza sativa (4)
Glycine max (4)
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Solanum lycopersicum (3)
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Listeria monocytogenes (2)
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unidentified (1)
Xenopus laevis (1)

Organisms

Homo sapiens (196)
Mus musculus (35)
Caenorhabditis elegans (7)
Saccharomyces cerevisiae (4)
Rattus norvegicus (2)
Pseudomonas mediterranea CFBP 5447 (1)
Thermotoga neapolitana Mcl (1)
Pseudomonas sp. Emmai (1)
Henipavirus nipahense (1)
Hyas araneus (1)
Pseudomonas taiwanensis (1)
Pseudomonas putida (1)
Apis mellifera (1)
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Drosophila melanogaster (1)
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human gut metagenome (1)
Danio rerio (1)
lake water metagenome (1)

Repository

biostudies-arrayexpress (567)
ENA (309)
geo (231)
pride (50)
EGA (38)
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dbGaP (2)
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NODE (1)

Tissue

B cell (9)
Cell culture (9)
Bone marrow (8)
Bone marrow cell (4)
Spleen (3)
Blood (2)
Brain (2)
Cell suspension culture (2)
Epithelial cell (2)
Cell line (1)
Bladder urothelial cell (1)
Cardiac blood vessel endothelial cell (1)
Cerebrospinal fluid (1)
Colon (1)
Embryonic fibroblast (1)
Fibroblast (1)
Gut (1)
HCT-116 cell (1)
Lung (1)
Lymph node (1)
Meniscus (1)
Myeloid cell (1)
Neuroblast proliferation (1)
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Peripheral blood lymphocyte (1)
Peripheral blood mononuclear cell (1)
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Skeletal muscle fiber (1)
Skin (1)

Disease

Acute leukemia (8)
Lymphoma (5)
Mantle cell lymphoma (4)
Chronic lymphocytic leukemia (4)
Normal (3)
Breast cancer (2)
Chronic lymphoid leukemia (1)
Primary acute lymphoblastic leukemia (1)
Pretreatment primary leukemia (1)
Oral squamous cell carcinoma (1)
Mantle cell lymphoma (1)
Adenoma (1)
Large cell neuroendocrine carcinoma (1)
Not applicable (1)
Low-stage neuroblastoma (1)
Crohn's disease (1)
Diffuse large B cell lymphoma (1)
Non-infected (1)
Obese (1)
Reference (1)
Psoroptes ovis infestation (1)
Osteosarcoma (1)
None (1)
Lymphoma (1)
Not Available (1)
Alzheimer's disease (1)
Amyloidosis (1)
B-cell lymphoma (1)
Follicular lymphoma (1)
Herpes simplex (1)

Technology Type

Mass Spectrometry (50)
Shotgun proteomics (28)
Bottom-up proteomics (10)
Affinity purification coupled with mass spectrometry proteomics (8)
Data-independent acquisition (6)
Data-dependent acquisition (3)
DiaPASEF (2)
Illumina HumanMethylation 450K (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, ILLUMINA (1)
NMR spectroscopy (1)
Mass spectrometry (1)
Affinity proteomics (1)
Gel-based experiment (1)

Instrument Platform

Illumina HiSeq 2500 (6)
Illumina NovaSeq 6000 (6)
Illumina HiSeq 2000 (4)
DNBSEQ-G400 (3)
Illumina HiSeq 4000 (3)
Q Exactive (3)
Orbitrap Fusion Lumos (2)
Q Exactive HF (2)
Affymetrix GCS 3000 (1)
GeneChip® Pico Kit (Affymetrix) (1)
Affymetrix Clariom™ S (400 Format) (1)
NuGEN Trio low input RNA-seq (1)
RNeasy Micro Kit (QIAGEN #74004) (1)
PALM Microbeam Rel. 4.9 with RoboMover microscope (Zeiss) (1)
MA900, Sony (1)
10x Chromium Controller (1)
Hybridization oven (1)
None (1)
Agilent scanner (1)
Picopure RNA kit (1)
Life Technology LCM system (1)
G2500A Hewlett Packard (1)
Other (1)
DNA Microarray Scanner BA [Agilent Technologies] (1)
Scanning hardware (1)
Illumina HiSeq X (1)
NextSeq 2000 (1)
Illumina MiSeq (1)
Instrument (1)
HFX Orbitrap (1)

Publication Date

2013 (91)
2010 (85)
2014 (69)
2012 (69)
2015 (66)
2008 (66)
2011 (59)
2016 (44)
2025 (40)
2026 (35)
2009 (33)
2021 (27)
2024 (26)
2019 (26)
2022 (25)
2020 (23)
2017 (22)
2007 (17)
2023 (15)
2018 (14)
2006 (11)
2005 (7)

CHEBI ID

CHEBI:145997 (1)
CHEBI:145996 (1)
CHEBI:145995 (1)
CHEBI:132553 (1)
CHEBI:80988 (1)
CHEBI:5395 (1)
CHEBI:80987 (1)
CHEBI:79324 (1)
CHEBI:79325 (1)
CHEBI:29028 (1)
CHEBI:80989 (1)
CHEBI:79311 (1)
CHEBI:79347 (1)
CHEBI:48430 (1)
CHEBI:26271 (1)
CHEBI:25094 (1)
CHEBI:22653 (1)
CHEBI:27570 (1)
CHEBI:18186 (1)
CHEBI:37684 (1)
CHEBI:26986 (1)
CHEBI:17234 (1)
CHEBI:28300 (1)
CHEBI:18257 (1)
CHEBI:24898 (1)
CHEBI:25017 (1)
CHEBI:15428 (1)
CHEBI:17268 (1)
CHEBI:28044 (1)
CHEBI:1148 (1)

Metabolite Name

5-benzoyloxypentyl glucosinolate (1)
4-benzoyloxybutyl glucosinolate (1)
3-benzoyloxypropyl glucosinolate (1)
Glucoibarin (1)
Glucoalyssin (1)
Glucoberteroin (1)
Glucobrassicin (1)
Glucoraphanin (1)
Gluconasturtiin (1)
Glucoerucin (1)
Glucolesquerellin (1)
3-Methyl-2-oxovalerate (1)
3-Hydroxy-butyrate (1)
2-Hydroxy-butyrate (1)
8-Methylthiooctyl glucosinolate (1)
7-Methylthioheptyl glucosinolate (1)
Isobutyrate (1)
Myo-Inositol (1)
Acetate (1)
Histidine (1)
Leucine (1)
Ketoleucine (1)
Glycine (1)
Valine (1)
Betaine (1)
Ornithine (1)
Acetylcarnitine (1)
Lysine (1)
Lactate (1)
Asparagine (1)

First Public Date

2014 (69)
2026 (33)
2025 (33)
2024 (32)
2019 (23)
2021 (21)
2020 (20)
2022 (17)
2018 (14)
2017 (14)
2015 (14)
2023 (9)
2016 (5)
2013 (5)

Classification

viruses (2)

Study status

Completed (1)

Study type

Transcription profiling by array (434)
RNA-seq of coding RNA (48)
Comparative genomic hybridization by array (26)
Transcription profiling by RT-PCR (10)
Other (7)
Unknown experiment type (6)
Methylation profiling by array (4)
RNA-seq of non coding RNA (4)
ChIP-seq (3)
RNA-seq of coding RNA from single cells (3)
Methylation profiling by high throughput sequencing (3)
Animal - High-throughput sequencing (2)
Genotyping by array (2)
MicroRNA profiling by array (2)
Proteomic profiling by array (2)
RNA-seq of total RNA (2)
RNA-seq of non coding RNA from single cells (1)
Animal - One-color microarray (1)
ChIP-chip by tiling array (1)
Human - High-throughput sequencing (1)
Plant - One-color microarray (1)
Human - One-color microarray (1)
RNAi profiling by array (1)
Observational (1)

Release Date

2022 (307)
2021 (269)
2023 (240)
2020 (221)
2025 (214)
2016 (205)
2015 (199)
2018 (196)
2019 (182)
2024 (180)
2014 (173)
2013 (172)
2017 (163)
2012 (144)
2010 (134)
2011 (128)
2008 (83)
2009 (68)
2007 (37)
2026 (24)
2006 (18)
2005 (11)
2002 (4)
2000 (2)
1998 (2)
2003 (1)
1999 (1)
1997 (1)

Lab affiliation

OncoProteomics Laboratory, Dept of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands (3)
Moffitt Cancer Center (2)
95 Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, 31077, France (1)
Assistant professor, School of Biological Sciences, Seoul National University. (1)
Bavarian Center for Biomolecular Mass Spectrometry at Klinikum rechts der Isar (BayBioMS@MRI), TUM School of Medicine and Health, Technical University of Munich (TUM), 81675 München, Germany (1)
Cambridge University (1)
Cardiovascular Proteomics Laboratory & Proteomics Unit Vascular Pathophysiology Area Centro Nacional de Investigaciones Cardiovasculares Melchor Fernández Almagro núm. 3 28029 Madrid (1)
Cell & Molecular Biology; St Jude Children's Research Hospital; Memphis, TN (1)
Centre Esther Koplowitz (CEK) (1)
Department of Biochemistry & Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton 3800, Australia (1)
Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, Melbourne, Victoria 3010, Australia (1)
Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore, 117543 (1)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (1)
Department of Chemical & Systems Biology Stanford University USA (1)
Department of Chemical & Systems Biology, Stanford University, USA (1)
Department of Chemistry, University of Rochester, United States (1)
Department of Food Science, Faculty of Science, University of Copenhagen, Rolighedsvej 30, DK-1958, Frederiksberg C, Denmark. (1)
Department of Genetics, Cell Bioliogy, & Anatomy Buckley Lab University of Nebraska Medical Center Omaha, Nebraska United States of America (1)
Department of Immunology and Cell biology, Université de Sherbrooke, 3201, Jean-Mignault, Sherbrooke, Québec, J1E 4K8, Canada (1)
Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa, 7925 (1)
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester MN (1)
Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02215, USA. (1)
Department of Pediatric Oncology Linde Program in Cancer Chemical Biology Dana-Farber Cancer Institute Boston, MA 02215 USA (1)
Department of Pediatric Oncology and Linde Program in Cancer Chemical Biology Dana-Farber Cancer Institute Boston, MA, USA (1)
Department of Pharmacology, University of São Paulo. São Paulo, SP, Brazil. (1)
Department of Physiology & Pharmacology, University of Calgary (1)
Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, CA, USA (1)
Dipartimento di Scienze Chimiche, Farmaceutiche ed Agrarie, Università degli Studi di Ferrara (1)
Head of the Department, Proteomics Core (1)
Laboratory Head Children's Cancer Institute Lowy Cancer Research Centre, UNSW Australia PO Box 81 Randwick 2031 Australia (1)

Location

Germany (1)

Keyword

Axitinib (1)
Sirolimus (1)
MTOR Inhibitors (1)
Temsirolimus (1)
Sunitinib (1)

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Thermotoga neapolitana Mcl

Thermotoga neapolitana Mcl Genome sequencing

PRJNA176358 | ENA

Expression data from MALD1 and MCL cases

Patients with conventional mantle cell lymphoma (MCL) show an aggressive clinical behavior. However, cases fulfilling the WHO criteria for MCL, but that remain asymptomatic without treatment, have been reported. In an attempt to understand this heterogeneity, we have compared 17 typical cases of MCL...

ORGANISM(S): Homo sapiens

2013-12-23 | E-GEOD-45717 | biostudies-arrayexpress

Affymetrix SNP array data for 29 MCL cases

DNA from four 29 cases, 38 tumor samples (23 PB, 12 LN, 1 Tonsil, 1 colonic biopsy, 1 spleen) and 29 normal DNA from the same patients were analyzed with Affymetrix SNP 6.0 platform for copy number alterations study. Affymetrix SNP arrays were performed according to the manufacturer's directions on ...

ORGANISM(S): Homo sapiens

2013-11-04 | E-GEOD-46969 | biostudies-arrayexpress

High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq)

SOX11 (Sex determining region Y-box 11) expression is specific for MCL as compared to other Non-HodgkinM-bM-^@M-^Ys lymphomas. However, the function and direct binding targets of SOX11 in MCL are largely unknown. We used high-resolution ChIP-Seq to identify the direct target genes of SOX11 in a geno...

ORGANISM(S): Homo sapiens

2014-08-07 | E-GEOD-52148 | biostudies-arrayexpress

SOX11 Gene Expression Profiling

The neural transcription factor SOX11 is overexpressed in aggressive lymphoid neoplasms mainly in mantle cell lymphoma (MCL), but its functional role in malignant B-cells is unknown. To identify target genes transcriptionally regulated by SOX11 in malignant lymphoid cells, we have used Gene Expressi...

ORGANISM(S): Homo sapiens

2013-04-04 | E-GEOD-34763 | biostudies-arrayexpress

Gene expression of mantle cell lymphoma-initiating cells from primary tumor samples

In this study we compared the expression of 30215 genes in mantle cell lymphoma-initiating cells (MCL-ICs) with mantle cell lymphoma-non-initiating cells (MCL-non-ICs) and B-cells from healthy donor Three samples each of MCL-ICs and MCL-non-ICs were isolated from aphresis of 3 mantle cell lymphoma p...

ORGANISM(S): Homo sapiens

2014-08-02 | E-GEOD-60023 | biostudies-arrayexpress

Mcl-1 is a key determinant of breast cancer cell survival

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

2015-08-07 | E-GEOD-66072 | biostudies-arrayexpress

Mantle Cell Lymphoma

Gene expression analyis of primary MCL including IGHV mutated and unmutated cases Gene set analysis was perfomed in MCL samples, comparing IGHV mutated cases vs. IGHV unmutated cases In total 38 MCL samples were processed with the HU133plus 2.0 microarray. Twenty four cases had a IGHV mutations and...

ORGANISM(S): Homo sapiens

2013-06-25 | E-GEOD-36000 | biostudies-arrayexpress

CCND2 rearrangements are the most frequent genetic events in Cyclin D1-negative mantle cell lymphoma [Affymetrix]

Cyclin D1-negative mantle cell lymphomas (MCL) are not well characterized, in part due to the difficulties in their recognition. SOX11 has been recently identified as a reliable biomarker of MCL, also expressed in the cyclin D1-negative variant. We investigated 40 lymphomas with MCL morphology and i...

ORGANISM(S): Homo sapiens

2012-12-19 | E-GEOD-42935 | biostudies-arrayexpress

MCL-1 Drives a Metabolic Dependency on Fatty Acid Oxidation in Cancer Independent of its Anti-Apoptotic Function

MCL-1 is an anti-apoptotic BCL-2 family protein essential to the survival of diverse cell types and is a major driver of cancer and chemoresistance. The unique oncogenic supremacy of MCL-1, as compared to its anti-apoptotic homologs, suggests that it has additional functions to complement apoptotic ...

ORGANISM(S): Mus musculus (Mouse)

2022-10-03 | PXD031364 | Pride

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