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TranscriptomicsRNA-seq analysis of HT-29, MCF10A, and MDA-MB-436 cells
RNA-seq data from HT-29 cells treated with IFN-M-NM-3 for 24 hr, MCF10A cells, and MDA-MB-436 cells. mRNA profiles of HT-29, MCF10A, and MDA-MB-436 were generated by deep sequencing using Illumina HiSeq 2000. All RNA sequencing data was generated by the Genomics Services Lab at the HudsonAlpha Insti...
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-45258 | biostudies-arrayexpress
TranscriptomicsExon arrays from HT-29, MCF10A, and MDA-MB-436 cells
Expression data from HT-29 cells treated with IFN-γ for 24 hr, MCF10A cells, and MDA-MB-436 cells. Total RNA was isolated with the RNeasy Mini Kit (Qiagen). Sense-strand cDNA synthesis, terminal labeling, and hybridization were performed using Ambion WT Expression Kit (Applied Biosystems, P/N 44252...
ORGANISM(S): Homo sapiens 
2013-08-06 | E-GEOD-45195 | biostudies-arrayexpress
TranscriptomicsTWEAK-treated time course in MDA-MB-436 cells
Tumor necrosis factor-related weak inducer of apoptosis, TWEAK, is a TNF superfamily member that mediates signaling through its receptor fibroblast growth factor inducible-14, Fn14. In tumor cell lines, TWEAK induces proliferation, survival and NF-kappaB signaling and gene expression that promote tu...
ORGANISM(S): Homo sapiens 
2013-10-04 | E-GEOD-42045 | biostudies-arrayexpress
GenomicsTumor derived MDA-MB-436 pLKO versus MDA-MB-436 shTONSL cells-enriched gene expression
Tumor derived MDA-MB-436 pLKO versus MDA-MB-436 shTONSL cells-enriched gene expression
PRJNA892638 | ENA
TranscriptomicsIdentification of a novel NF-kB target gene in human triple-negative breast cancer cells
Analysis of human triple-negative breast cancer cells (TNBCs) which have high NF-kB activity. Proteins derived from NF-κB target genes might be molecular targets for cancer therapy. Results provide new insights into tumor proliferation mechanisms. Exp. 1: Mock MDA-MB-436 cells vs. MDA-MB-436 cells ...
ORGANISM(S): Homo sapiens 
2015-02-20 | E-GEOD-56812 | biostudies-arrayexpress
GenomicsOverexpression of miR-200c/141 and miR-200b/200a/429 in MDA-MB-436 cells
Overexpression of miR-200c/141 and miR-200b/200a/429 in MDA-MB-436 cells
PRJNA1091958 | ENA
TranscriptomicsExpression data from breast cancer cells overexpressing NF1-C2
NF1-C2 suppresses tumorigenesis and epithelial-to-mesenchymal transition by repressing FoxF1. We used microarray to identify direct targets for NF1-C2. The human breast tumor cell line MDA-MB-436 were stably transfected with an expression plasmid including NF1-C2. RNA from these cells and wildtype c...
ORGANISM(S): Homo sapiens 
2010-03-09 | E-GEOD-17636 | biostudies-arrayexpress
TranscriptomicsTumor derived MDA-MB-436 pLKO versus MDA-MB-436 shTONSL cells-enriched gene expression
To study TONSL regulated genes in neoplastically transformed cells, we established tumor derived MDA-MB-436 cell lines in which TONSL is been knocked down by shRNA.
ORGANISM(S): Homo sapiens 
2023-10-31 | GSE216239 | GEO
TranscriptomicsExon arrays from HT-29, MCF10A, and MDA-MB-436 cells
Expression data from HT-29 cells treated with IFN-γ for 24 hr, MCF10A cells, and MDA-MB-436 cells.
ORGANISM(S): Homo sapiens 
2013-08-06 | GSE45195 | GEO
TranscriptomicsIndole-3-Carbinol Preferentially Target ERα-Positive Breast Cancer Cells.
Indole-3-carbinol (I3C) is a natural anti-carcinogenic compound found at high concentrations in Brassica vegetables. ER-positive cell lines demonstrated the greatest sensitivity to the anti-tumor effects of I3C compared to ER-negative breast cancer cell lines. Gene expression analysis was performed ...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-55897 | biostudies-arrayexpress
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