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TranscriptomicsTranscription profiling of mouse hindlimb muscle, comparison of wild type and mdx mice, 7 to 112 Day
Determination of gene expression changes in hindlimb muscle (gastrocnemius/soleus) of mdx (dystrophin-deficient) mice at postnatal ages 7, 14, 23, 28, 56, and 112.
ORGANISM(S): Mus musculus 
2007-10-05 | E-GEOD-1025 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse extraocular muscle, comparison of wild type and mdx mice, 14 to 112 Days
Determination of gene expression changes in extraocular muscle of mdx (dystrophin-deficient) mice at postnatal ages 14, 28, 56, and 112 days. 3 independent replicates/age/strain. Data form part of publications: Human Molecular Genetics 12:1813-1821, 2003 and FASEB Journal 17: 893-895, 2003 (on-lin...
ORGANISM(S): Mus musculus 
2007-10-04 | E-GEOD-1008 | biostudies-arrayexpress
TranscriptomicsTime-course of mdx and wild type mice
Time-course microarray data set of mdx and wild type mice ranging from 1-20 weeks of age Keywords: time-course
ORGANISM(S): Mus musculus 
2010-05-27 | E-GEOD-1574 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of skeletal muscle from wild type and mdx mice at three time points
In this study, in order to minimize the genetic variability of muscle samples we have used two approaches. First, we have analyzed the gene expression profile from a single skeletal muscle, the medial gastrocnemius (MG), and not from a pool of different muscles which could have different expression ...
ORGANISM(S): Mus musculus 
2009-04-16 | E-MEXP-1623 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse diaphragm, comparison of wild type and mdx mice, 7 to 112 days
Determination of gene expression changes in diaphragm muscle of mdx (dystrophin-deficient) mice at postnatal ages 7, 14, 23, 28, 56, and 112 days. 3 independent replicates/age/strain. Data form part of publication: Human Molecular Genetics 13:257-269, 2004.
ORGANISM(S): Mus musculus 
2007-10-05 | E-GEOD-1026 | biostudies-arrayexpress
TranscriptomicsRNA-seq comparison of fibro-adipogenic progenitors (FAPs) from wild type, mdx and cardiotoxin-injured mice
We purified FAPs from the hind limbs of wild type, mdx and cardiotoxin-injured mice in order to unveil changes in their transcriptomes. RNA was isolated directly from sorted cells and analyzed by 3’ RNA sequencing.
ORGANISM(S): Mus musculus 
2019-06-20 | E-MTAB-8040 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse extraocular and hindlimb muscle to determine gene expression changes in extraocular and hindlimb (gastrocnemius/soleus) of mdx (dystrophin-deficient) mice at postnatal day 56
Determination of gene expression changes in extraocular and hindlimb (gastrocnemius/soleus) of mdx (dystrophin-deficient) mice at postnatal day 56. 5 independent replicates/muscle group/strain.
ORGANISM(S): Mus musculus 
2007-10-09 | E-GEOD-1472 | biostudies-arrayexpress
TranscriptomicsArray profiling of dystrophin-deficient mice with a secondary glycosylation defect
A deletion in the CMAH gene in humans occurred approximately 3.5 million years ago. This resulted in the inactivation of the CMP-Neu5Ac hydroxylase enzyme, and hence, in the specific deficiency in N-glycolylneuraminic acid (Neu5Gc), a form of sialic acid, in all modern humans. Although there is evid...
ORGANISM(S): Mus musculus 
2010-07-31 | E-GEOD-16438 | biostudies-arrayexpress
TranscriptomicsSmall RNA-sequencing of Fibro-Adipogenic Progenitors (FAPs) upon Histone Deacetylase inhibition in young mdx mice
Fibro-adipogenic progenitors (FAPs) are emerging cellular components of the skeletal muscle regenerative environment. The alternative functional phenotype of FAPs - either supportive of muscle regeneration or promoting fibro-adipogenic degeneration - is a key determinant in the pathogenesis of muscu...
ORGANISM(S): Mus musculus 
2014-04-23 | E-GEOD-51933 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse mdx animals expressing high levels of utrophin therapeutic implications for DMD
Duchenne Muscular Dystrophy (DMD) is a fatal muscle wasting disorder caused by dystrophin deficiency. Previous work suggested that increased expression of the dystrophin-related protein utrophin in the mdx mouse model of DMD can prevent dystrophic pathophysiology. Physiological tests showed that t...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7187 | biostudies-arrayexpress
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