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The transition from the non-maternal to the maternal state is characterized by a variety of CNS alterations that support the care of offspring. The septum (including lateral and medial portions) is a brain region previously linked to various emotional and motivational processes, including maternal c...
ORGANISM(S): Mus musculus 
The Otx2 homeobox transcription factor is essential for gastrulation and early neural development. We generated Otx2 conditional knockout (cKO) mice to investigate its roles in telencephalon development after E9.0. We conducted transcriptional profiling and in situ hybridization to identify genes de...
ORGANISM(S): Mus musculus 
By precisely dissected MS for proteomics, we found that donepezil remarkably restored (at high dose), even elevated (at low dose) the level of vacuolar protein sorting-associated protein 37D (VP37D), an autophagy-related protein, in hTauMS mice.
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD023297 | Pride
Coordinated gene expression changes across the CNS help to produce the mammalian maternal phenotype. Lateral septum (LS) is a brain region critically involved with aspects of maternal care, and we recently examined gene expression of whole septum (LS and medial septum) in selectively bred maternal ...
ORGANISM(S): Mus musculus 
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