Medium optimization

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Instrument Platform

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2025 (30)
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UNIPROT ID/AC

A0A0A0MS51 (6)
B4DPR2 (6)
B7Z556 (6)
B7Z9A0 (6)
B7ZKJ8 (6)
C9JV77 (6)
E7ETN3 (6)
E9PFZ2 (6)
F8W696 (6)
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CHEBI ID

CHEBI:15741 (9)
CHEBI:18012 (9)
CHEBI:18186 (8)
CHEBI:15891 (8)
CHEBI:17172 (8)
CHEBI:15428 (8)
CHEBI:28044 (7)
CHEBI:16704 (7)
CHEBI:17509 (7)
CHEBI:15971 (7)
CHEBI:17568 (7)
CHEBI:16335 (7)
CHEBI:27897 (7)
CHEBI:16643 (7)
CHEBI:17295 (7)
CHEBI:17368 (7)
CHEBI:16708 (6)
CHEBI:17750 (6)
CHEBI:17115 (6)
CHEBI:18295 (6)
CHEBI:16856 (6)
CHEBI:16040 (6)
CHEBI:15611 (6)
CHEBI:17203 (6)
CHEBI:16015 (6)
CHEBI:17053 (6)
CHEBI:16449 (6)
CHEBI:15940 (6)
CHEBI:16414 (6)
CHEBI:15354 (6)

Metabolite Name

Uracil (13)
L-Phenylalanine (11)
Indole (10)
Betaine (9)
L-Asparagine (9)
Choline (9)
Adenosine (9)
Histamine (9)
Guanosine (9)
L-Cystine (8)
L-Alanine (8)
Spermine (8)
Piperidine (8)
L-Histidine (8)
Nicotinamide (8)
Cytosine (8)
L-Glutamine (8)
L-Serine (8)
Cytidine (8)
L-Valine (8)
Isonicotinic acid (7)
Diethanolamine (7)
L-Ornithine (7)
L-Homocitrulline (7)
4-Hydroxybenzaldehyde (7)
L-Arginine (7)
L-Lysine (7)
Melibiose (7)
L-Glutamic acid (7)
Spermidine (7)

First Public Date

2026 (11)
2025 (11)
2021 (5)
2014 (5)
2024 (4)
2018 (3)
2015 (3)
2023 (2)
2022 (2)
2019 (2)
2013 (2)
2020 (1)
2016 (1)
2011 (1)

Modelling Approach

Constraint-based model (1)

Lab affiliation

1VIB-UGent Center for Medical Biotechnology, VIB, 9052 Ghent, Belgium 2Department of Biomolecular Medicine, Ghent University, 9052 Ghent, Belgium (3)
Staff Scientist Biological Systems & Engineering Division Lawrence Berkeley National Laboratory Berkeley CA 94720 (3)
CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad - 500007, India (2)
Lee Kong Chian School of Medicine, School of Biological Sciences, Nanyang Technological University, Singapore (2)
North Carolina State University (2)
AgriBio centre, Department of Economic Development, government of Victoria, Australia (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich, Gregor-Mendel-Strasse 4, D-85354 Freising, Germany (1)
Biological Mass Spectrometry Facility, Center for Biomedical Research Support, The University of Austin at Texas (1)
CSO, Bioaster, France (1)
Cancer Research UK Manchester Institute (1)
Cedars-Sinai Medical Center (1)
Center for Theragnosis, Korea Institute of Science and Technology, Seoul, Korea (1)
Centre de Recherches en Cancérologie de Toulouse; INSERM U1037, team 17 PI3K isoforms, signalling and cancerogenesis (1)
College of life Sciences, Sichuan Normal University, Chengdu, Sichuan 610101, China (1)
D.Sc., associate professor Head of Laboratory of Genetic Engineering Research Institute of Physical-Chemical Medicine (1)
Departament de Bioquímica i Biologia Molecular, Facultat de Ciències Biològiques, Universitat de València, Burjassot (València), Spain (1)
Department of Biology, Chair of Molecular Genetics and Microbiology, University of Ljubljana, Slovenia (1)
Department of Genome Sciences, University of Washington, Seattle, WA, USA (1)
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden (1)
Department of Medicine, Division of Canadian Centre for Rural and Agricultural Health, College of Medicine, University of Saskatchewan (1)
Department of Microgravity and Translational Regenerative Medicine, Otto-von-Guericke University Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany (1)
Department of Molecular Mechanisms of Disease, University of Zurich, CH-8057 Zurich, Switzerland (1)
Department of Physiological Sciences, College of Veterinary Medicine, University of Florida (1)
Department of Urology, Radboud Institute for Medical Innovation, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA, Nijmegen, The Netherlands. (1)
Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, P. R. China (1)
Dept. of Proteomics and Signal Transduction Max Planck Institute of Biochemistry (1)
Director and Professor, School of Pharmaceutical Sciences (1)
German Cancer Reseach Center (DKFZ) (1)
Indiana University School of Medicine (1)
Institut Pasteur - CNRS USR 2000 Mass Spectrometry for Biology Unit 28, rue du Dr. Roux 75 015 Paris (1)

IsPrivate

False (1)

Model Flag

Non Kinetic (1)

Classification

bacteria (3)

Study type

Transcription profiling by array (31)
ChIP-seq (5)
RNA-seq of coding RNA (5)
Spatial transcriptomics by high-throughput sequencing (4)
Genotyping by array (3)
RNA-seq of coding RNA from single cells (3)
Cell line - High-throughput sequencing (2)
Other (2)
RNA-seq of total RNA (2)
RNA-seq of non coding RNA from single cells (1)
ChIP-chip by tiling array (1)
Human - Single-cell sequencing (1)
Human - High-throughput sequencing (1)
ChIP-chip by array (1)
Transcription profiling by RT-PCR (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of non coding RNA (1)

Release Date

2025 (189)
2022 (173)
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2021 (126)
2020 (108)
2019 (97)
2018 (72)
2017 (64)
2015 (51)
2016 (50)
2026 (44)
2014 (40)
2013 (34)
2012 (25)
2010 (25)
2011 (17)
2008 (5)
2007 (4)
2006 (4)
2009 (3)
2005 (1)
2003 (1)
2002 (1)
2000 (1)

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Deep longitudinal multi-omics analysis of Bordetella pertussis cultivated in bioreactors highlights medium starvations and transitory metabolisms, associated to vaccine antigen biosynthesis variations and global virulence regulation

Bordetella pertussis is the bacterial causative agent of whooping cough, a serious respiratory illness. An extensive knowledge on its virulence regulation and metabolism is a key factor to ensure pertussis vaccine manufacturing process robustness. The aim of this study was to refine our ...

2023-02-21 | MTBLS5762 | MetaboLights

Variations of secretome profiles according to conditioned medium preparation: the example of human mesenchymal stem cell derived adipocytes

One challenging point in analysing cellular secretome collected as conditioned medium is cross contamination by cell culture media components, especially bovine serum proteins. A common approach for serum removal is to wash the cells, an alternative is to grow cells using serum-free conditions. Give...

ORGANISM(S): Homo sapiens (Human)

2015-07-03 | PXD002217 | Pride

Adipocyte/conditioned medium/mesenchymal stem cell /secretome

E. coli ATCC 8739 transcriptomics under culture medium optimization and adaptive laboratory evolution for glycerol consumption

PRJNA591155 | ENA

Employing active learning in the optimization of culture medium for mammalian cells.

Not available

S-EPMC10229643 | biostudies-literature

Effect of amino acid availability on vitamin B12 production in Lactobacillus reuteri

Recent functional genomics and genome-scale modeling approaches indicated that B12 production in Lactobacillus reuteri could be improved by medium optimization. Here we show that a series of systematic single amino acid omissions could significantly modulate the production of B12 from nearly undetec...

ORGANISM(S): Lactobacillus reuteri F275

2010-05-17 | E-GEOD-13391 | biostudies-arrayexpress

MediaAssist: database to support the design and optimization of cell culture medium.

Not available

S-EPMC12808543 | biostudies-literature

Response Surface Methodology-Genetic Algorithm Based Medium Optimization, Purification, and Characterization of Cholesterol Oxidase from Streptomyces rimosus.

Not available

S-EPMC6053457 | biostudies-literature

Medium optimization based on comparative metabolomic analysis of chicken embryo fibroblast DF-1 cells.

Not available

S-EPMC9070647 | biostudies-literature

Response surface optimization of culture medium for enhanced docosahexaenoic acid production by a Malaysian thraustochytrid.