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GenomicsMegacomplex protects ESR1 from degradation by Fulvestrant in epithelial ovarian cancer
Megacomplex protects ESR1 from degradation by Fulvestrant in epithelial ovarian cancer
PRJNA1111537 | ENA
GenomicsMegacomplex protects ESR1 from degradation by Fulvestrant in epithelial ovarian cancer
Ovarian cancer, a significant contributor to cancer-related mortality, often exhibits limited responsiveness to hormonal therapies targeting the estrogen receptor (ESR1). This study aimed to elucidate the mechanisms behind ESR1 resistance to the therapeutic drug Fulvestrant (ICI182780 or ICI). We id...
ORGANISM(S): Homo sapiens 
2025-05-15 | GSE267459 | GEO
UnknownThe Megacomplex protects ER-alpha from degradation by Fulvestrant in epithelial ovarian cancer.
Not available
S-EPMC12276986 | biostudies-literature
UnknownStructural bioinformatic study of human mitochondrial respiratory integral membrane megacomplex and its AlphaFold3 predicted water-soluble QTY megacomplex analog.
Not available
S-EPMC11950790 | biostudies-literature
ProteomicsPhotosynthetic Megacomplex in Synechosystis 6803
Phycobilisomes capture light energy and feed into reaction centers in cyanobacteria and red algae. Their ability to capture light across a broad spectral range, distinct from those of the chlorophylls and carotenoids, expand photosynthetic solar energy transformation globally. The energy transfer fr...
ORGANISM(S): Synechocystis sp. PCC 6803 
2013-11-29 | PXD000545 | Pride
Photosystem i Phycobilisomes Cyanobacteria Photosystem ii Cross-linking Lc-ms/ms 
UnknownPhycobilisomes supply excitations to both photosystems in a megacomplex in cyanobacteria.
Not available
S-EPMC3947847 | biostudies-literature
UnknownArchitecture and functional regulation of a plant PSII-LHCII megacomplex.
Not available
S-EPMC11640958 | biostudies-literature
UnknownStructure of a unique PSII-Pcb tetrameric megacomplex in a chlorophyll <i>d</i>-containing cyanobacterium.
Not available
S-EPMC10889353 | biostudies-literature
UnknownStructure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex.
Not available
S-EPMC9931586 | biostudies-literature
UnknownThe identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis.
Not available
S-EPMC1785240 | biostudies-literature
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