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This project focused in the proteomic characterization of the secreted proteome of a Rv1002c (Protein mannosyltransferase) knock-out mutant and its wild type counterpart. The analysis was carried out using a M. tuberculosis ΔleuDΔpanCD auxotroph Rv1002c wild type compared to M. tuberculosis ΔleuDΔp...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2019-04-09 | PXD011081 | Pride
Tuberculosis remains one of the most difficult to control infectious diseases in the world. Many different factors contribute to the complexity of this disease. These include the ability of the host to control the infection which may directly relate to nutritional status, presence of co-morbidities ...
ORGANISM(S): Mycobacterium tuberculosis 
2018-04-23 | PXD005687 | Pride
This project describes the isoniazid (INH) resistance acquisition event in Mycobacterium tuberculosis (Mtb) from the proteomics perspective. In this way, an exploration of the protein differences, comparing clonal INH susceptible (INHs) and INHr pairs of Mtb were evaluated. One clonal clinical and o...
ORGANISM(S): Mycobacterium tuberculosis 
2018-06-25 | PXD009549 | Pride
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