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TranscriptomicsGene Expression Profiles Predict Postpartum-onset Depression Patients with Treatment-Resistant Depression Patients with Treatment-Resistant Depression
To identify early predictive biomarkers for postpartum depression using peripheral blood gene expression profiles RNA was isolated from peripheral blood collected in Tempus RNA tubes (Applied Biosystems, Darmstadt, Germany) at all three investigated time points for each woman in the discovery sample...
ORGANISM(S): Homo sapiens 
2013-03-29 | E-GEOD-45603 | biostudies-arrayexpress
TranscriptomicsPax versus tempus expression profile differences
The main aim of the study was to compare genome-wide gene expression profiles obtained from the two widely used commercially available whole blood RNA collection systems - PAXgeneTM and TempusTM tubes. Comparisons of present call rates, variances, correlations and influence of globin reduction acros...
ORGANISM(S): Homo sapiens 
2012-01-15 | E-GEOD-34039 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles Predict Infliximab Treatment Response in Patients with Treatment-Resistant Depression
To further explore predictors and targets of response to infliximab, differential gene expression was examined at baseline and after 6 and 24 hours and 2 weeks after the first infusion of infliximab in TRD patients who were infliximab responders versus nonresponders, and compared to placebo-treated ...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-45468 | biostudies-arrayexpress
TranscriptomicsTranscriptional landscape of aging in humans
We carried out blood transcriptome-wide association studies and replicated results to identify genes whose expression differs across the human aging spectrum. The transcriptional landscape of aging in humans
ORGANISM(S): Homo sapiens 
2014-06-15 | E-GEOD-58137 | biostudies-arrayexpress
TranscriptomicsTranscriptomics analysis of human of stage-specific atherosclerotic plaques: Signature mRNA-miRNA profile of disease severity
Detection of the altered expression of inflammation associated genes in patients’ blood can provide information regarding the stage of atherosclerotic plaque without undergoing invasive procedures. In the current study, the expression levels of miRNAs within the early stage and advanced stage athero...
ORGANISM(S): Homo sapiens 
2021-06-01 | E-MTAB-10051 | biostudies-arrayexpress
TranscriptomicsTranscriptomics analysis of human of stage specific atherosclerotic plaques: Signature mRNA-miRNA profile of disease severity (mRNA data)
Detection of the altered expression of inflammation associated genes in patients’ blood can provide information regarding the stage of atherosclerotic plaque without undergoing invasive procedures. In the current study, the expression levels of mRNAs within the early stage and advanced stage atheros...
ORGANISM(S): Homo sapiens 
2021-06-01 | E-MTAB-10052 | biostudies-arrayexpress
TranscriptomicsInvestigating the first genomic response to stress – insights into the etiology and pathophysiology of major depression
While exposure to adverse life events and subsequent dysregulation of the stress hormone response broadly confer risk for depression, the specific molecular mechanisms mediating this risk are poorly understood. Through pharmacologic activation of the stress hormone response in blood cells we demonst...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-46743 | biostudies-arrayexpress
UnknownDeath following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic.
Not available
S-EPMC10364875 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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