Sort   by:  
 Page size 
TranscriptomicsHigh resolution Hi-C analysis in S. pombe reveals fundamental elements of genome architecture [Expression Array]
Eukaryotic genomes are folded into three-dimensional structures that govern diverse hromosomal procsses. Studeis in Drosophila and mammals have revealed large self-associating tomological domains whose borders are enriched in cohesin/CTCF factors that are required for long-range intrations. Howeve...
ORGANISM(S): Schizosaccharomyces pombe 
2014-10-22 | E-GEOD-57159 | biostudies-arrayexpress
TranscriptomicsHigh resolution Hi-C analysis in S. pombe reveals fundamental elements of genome architecture (NGS)
Eukaryotic genomes are folded into a hierarchy of three-dimensional structures that impact nuclear functions, including transcription, replication, and repair1-3. Studies in Drosophila and mammals have revealed megabase-sized topologically associated domains (TADs) within chromosomes, which in turn ...
ORGANISM(S): Schizosaccharomyces pombe 
2014-10-22 | E-GEOD-57316 | biostudies-arrayexpress
TranscriptomicsChIP-Chip
The regulation of protein-coding and noncoding RNAs is linked to nuclear processes including chromatin modifications and gene silencing. However, the mechanisms that distinguish RNAs and mediate their functions are poorly understood. We describe a nuclear RNA processing network in fission yeast with...
ORGANISM(S): Schizosaccharomyces pombe 
2013-11-21 | E-MTAB-1962 | biostudies-arrayexpress
TranscriptomicsRNAi triggered by specialized machinery silences developmental genes and retrotransposons (RNA-Seq)
RNAi is a conserved mechanism in which small interfering RNAs (siRNAs) guide the degradation of cognate RNAs, but also promote heterochromatin assembly at repetitive DNA elements such as centromeric repeats. However, the full extent of RNAi functions and its endogenous targets have not been explored...
ORGANISM(S): Schizosaccharomyces pombe 
2012-11-26 | E-GEOD-41634 | biostudies-arrayexpress
TranscriptomicsAn SRY homolog cooperates with a transposon-derived CENP-B protein to control sex-specific directed recombination
Occupancy profiling of Myc tagged Mc protein in fission yeast. Agilent 60mer array was used to analyze DNA recovered by immunoprecipitation of Mc-myc protein from culture of fission yeast.
ORGANISM(S): Schizosaccharomyces pombe 
2011-11-21 | E-GEOD-32996 | biostudies-arrayexpress
GenomicsHDAC mediated suppression of histone turnover promotes epigenetic stability of heterochromatin
Analysis of histone H3 turnover in wild-type and mutant fission yeast cells by using MNase-ChIP-chip Exponentially growing cultures of fission yeast cells expressing an ectopic copy of FLAG tagged histone H3 under the control of inv1 promoter were synchronized and expression of H3-FLAG was induced b...
ORGANISM(S): Schizosaccharomyces pombe 
2013-04-21 | E-GEOD-45378 | biostudies-arrayexpress
Sort   by:  
 Page size