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GenomicsChIP-seq analysis of the cAMP binding protein (CRP) in Enteroaggregative Escherichia coli 042
ChIP-seq experiments were carried out in Enteroaggregative Escherichia coli 042. Wildtype 042 cells were grown to mid-log phase in LB medium, before being crosslinked with 1% formaldehyde and sonicated to lyse cells and shear DNA. Immunocomplexes were established using anti-FLAG antibodies. The immu...
ORGANISM(S): Escherichia coli 
2025-07-09 | E-MTAB-14748 | biostudies-arrayexpress
ProteomicsNCLX proximity biotinylation screen
The mitochondrial sodium/calcium exchanger, NCLX, is critical to maintaining mitochondrial calcium homeostasis, yet little remains known about the mechanisms regulating its function. Here, we performed proximity biotinylation screening to identify the NCLX interactome and potential protein regulator...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000093004 | MassIVE
TranscriptomicsSenescent and myofibroblastic cancer-associated fibroblasts share a contractile phenotype regulated by NOX4 generation of reactive oxygen species in the tumour microenvironment
Cancer associated fibroblasts characterized by an myofibroblastic phenotype play a major role in the tumour microenvironment, being associated with poor prognosis. We found that this cell population is made in part by senescent fibroblasts in vivo. As senescent fibroblasts and myofibroblasts have be...
ORGANISM(S): Homo sapiens 
2017-06-01 | E-MTAB-3101 | biostudies-arrayexpress
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