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TranscriptomicsHuman Monocytes to M-CSF differentiated Macrophages
This dataset was created to study M-CSF dependent in vitro differentiation of human monocytes to macrophages as a model process to demonstrate that independent component analysis (ICA) is a useful tool to support and extend knowledge-based strategies and to identify complex regulatory networks or no...
ORGANISM(S): Homo sapiens 
2011-11-07 | E-GEOD-9801 | biostudies-arrayexpress
UnknownOverexpression of the Drosophila ATR homologous checkpoint kinase Mei-41 induces a G2/M checkpoint in Drosophila imaginal tissue.
Not available
S-EPMC6125995 | biostudies-literature
GenomicsWhole-genome landscape of histone H2AX and M-NM-3-H2AX
Phosphorylation of the histone variant H2AX forms M-NM-3-H2AX that marks DNA double-strand break (DSB). Here we generated the sequencing-based maps of H2AX and M-NM-3-H2AX positioning in resting and proliferating cells before and after ionizing irradiation. Genome-wide locations of possible endoge...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-25577 | biostudies-arrayexpress
UnknownNegative regulation of G2-M by ATR (mei-41)/Chk1(Grapes) facilitates tracheoblast growth and tracheal hypertrophy in Drosophila.
Not available
S-EPMC5953539 | biostudies-literature
GenomicsChip-seq analysis of meiotic Cohesin complexes (mei-Cohesins) subunits, CTCF, and BORIS/CTCFL in Macaca fascicularis testis
The study involved chromatin IP analyzed by high-throughput sequencing analysis using purifird germ cells from M. fascucularis testis M. fascicularis is a monkey with non-seasonal male germ cells production, and the most popular primate for preclinical animal studies. The goal of the study was to in...
ORGANISM(S): Macaca fascicularis 
2022-09-30 | GSE118006 | GEO
MetabolomicsDetermination of Abundant Metabolite Matrix Adducts Illuminates the Dark Metabolome of MALDI-Mass Spectrometry Imaging Datasets
Spatial metabolomics using mass spectrometry imaging (MSI) is a powerful tool to map hundreds to thousands of metabolites in biological systems. One major challenge in MSI is the annotation of m/z values, which is substantially complicated by background ions introduced throughout the c...
2021-06-15 | MTBLS954 | MetaboLights
GenomicsMeiotic recombination cold spots in chromosomal cohesion sites [ChIP-Seq]
Meiotic chromosome architecture called M-bM-^@M-^\axis-loop structuresM-bM-^@M-^] and histone modifications have been demonstrated to regulate the Spo11-dependent formation of DNA double-strand breaks (DSBs) that trigger meiotic recombination. Using genome-wide chromatin immunoprecipitation (ChIP) a...
ORGANISM(S): Saccharomyces cerevisiae 
2014-03-31 | E-GEOD-52862 | biostudies-arrayexpress
ProteomicsProteomic analysis reveals that Sulfamethoxazole induces oxidative stress in M. tuberculosis
These sixteen RAW files represent twelve different samples submitted to the Centre for Proteomic and Genomic Research in Cape Town, South Africa, for shotgun proteomics analysis. Two different strains of Mycobacterium tuberculosis are included: --K636, a "Beijing" variant susceptible to TB drugs t...
ORGANISM(S): Mycobacterium Tuberculosis (ncbitaxon:1773) 
2018-03-25 | MSV000082209 | MassIVE
TranscriptomicsExpression data from control and colicin M treated E. coli MG1655 culture
Among colicin producing E. coli, colicin M producing strains are the most frequently present in natural populations. Bacteria must be able to sense and respond to unfavourable conditions, resulting in adaptive responses. To gain insight into colicin M ecological role and the purposes related to anti...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2012-11-26 | E-GEOD-37026 | biostudies-arrayexpress
UnknownMEI-1/MEI-2 katanin-like microtubule severing activity is required for Caenorhabditis elegans meiosis.
Not available
S-EPMC316576 | biostudies-literature
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