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GenomicsNKI-AvL TGO DAC
Data Access Committee EGAC00001001051
EGAC00001001051 | EGA
TranscriptomicsAltered microRNA expression associated with chromosomal and epigenetic changes contributes to cervical carcinogenesis
Little is known about the alterations in microRNA (miRNA) expression patterns during the consecutive stages of cervical cancer development and their association with chromosomal instability and epigenetic changes. We integrated miRNA expression profiles in normal cervical squamous epithelium, high-g...
ORGANISM(S): Homo sapiens 
2012-06-27 | E-GEOD-30656 | biostudies-arrayexpress
GenomicsQuantification of chromosomal copy number aberrations by shallow whole-genome sequencing
Detection of DNA copy number aberrations by shallow whole-genome sequencing (WGS) faces many challenges including lack of completion and errors in the human reference genome, repetitive sequences, polymorphisms, variable sample quality, and biases in the sequencing procedures. Formalin-fixed paraffi...
EGAS00001000642 | EGA
Genomicsena-DATASET-VUMC-CCA-18-03-2014-11:02:55:717-600 - samples
Description not provided
EGAD00001000780 | EGA
TranscriptomicsMultiple genes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression
Chromosomal instability (CIN) is the hallmark of colorectal adenoma to carcinoma progression in 85% of cases, with 20q gain as the most prominent aberration. Yet, the oncogenes at this chromosomal gain are still largely unknown. Here, we aimed to identify oncogenes at 20q involved in colorectal aden...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-8067 | biostudies-arrayexpress
Genomicsena-DATASET-JHU-SOM-01-09-2017-17:11:13:045-143 - samples
The dataset for Direct Detection of Early-Stage Cancers using Circulating Tumor DNA includes 602 bam files from next-generation sequencing on the Illumina HiSeq2500 or MiSeq. The samples analyzed include cancer cell lines as well as plasma and tissue specimens from healthy individuals and patients ...
EGAD00001003601 | EGA
GenomicsDirect Detection of Early-stage Cancers Using Circulating Tumor DNA
Early detection and intervention are likely to be the most effective means for reducing morbidity and mortality of human cancer. However, development of methods for noninvasive detection of early-stage tumors has remained a challenge. We have developed an approach called targeted error correction se...
EGAS00001002577 | EGA
GenomicsDAC for Direct Detection of Early-stage Cancers Using Circulating Tumor DNA
Data Access Committee EGAC00001000701
EGAC00001000701 | EGA
TranscriptomicsLack of microRNA-101 causes E-cadherin expression and function deregulation through EZH2 up-regulation in gastric cancer
Background & Aims: E-cadherin expression disruption is commonly observed in epithelial cancers and metastasis. Such event is also recognized as a crucial step in gastric cancer (GC) initiation and progression. As aberrant expression of microRNAs often perturb the normal expression and function of pi...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-33743 | biostudies-arrayexpress
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