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TranscriptomicsSeparation of DNA replication from the assembly of break-competent meiotic chromosomes
The meiotic cell division reduces the chromosome number from diploid to haploid to form gametes for sexual reproduction. Although much progress has been made in understanding meiotic recombination and the two meiotic divisions, the processes leading up to recombination, including the prolonged pre-m...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-14 | E-GEOD-35667 | biostudies-arrayexpress
TranscriptomicsSMC5/6 facilitates joint molecule resolution and stepwise loss of cohesin to promote meiotic chromosome segregation
During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation. While meiotic functions of the cohesin and condensin complexes have been delineated, the role of the third SMC complex, Smc5/6, rema...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-27 | E-GEOD-44852 | biostudies-arrayexpress
TranscriptomicsMeiotic cohesins modulate chromosome compaction during meiotic prophase in fission yeast
The meiotic cohesin Rec8 is required for the stepwise segregation of chromosomes during the two rounds of meiotic division. By directly measuring chromosome compaction in living cells of the fission yeast Schizosaccharomyces pombe, we found an additional role for the meiotic cohesin in the compactio...
ORGANISM(S): Schizosaccharomyces pombe 
2010-07-01 | E-GEOD-5284 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila melanogaster spermatogenesis: mitotic, meiotic and post-meiotic cells
We conducted a genome-wide expression analysis of wild-type males using three cell populations isolated from mitotic, meiotic and post-meiotic phases of spermatogenesis in Drosophila melanogaster. Our approach was to directly isolate testis regions enriched with RNAs from each of the three specific ...
ORGANISM(S): Drosophila melanogaster 
2009-11-28 | E-GEOD-18502 | biostudies-arrayexpress
TranscriptomicsMeiotic recombination cold spots in chromosomal cohesion sites [ChIP-chip]
Meiotic chromosome architecture called M-bM-^@M-^\axis-loop structuresM-bM-^@M-^] and histone modifications have been demonstrated to regulate the Spo11-dependent formation of DNA double-strand breaks (DSBs) that trigger meiotic recombination. Using genome-wide chromatin immunoprecipitation (ChIP) a...
ORGANISM(S): Schizosaccharomyces pombe 
2014-03-31 | E-GEOD-52858 | biostudies-arrayexpress
TranscriptomicsTranscriptomic regulation and methylation of the Lysine4 of Histone H3 during meiosis
This SuperSeries is composed of the following subset Series: GSE10836: Meiotic time course of Histone H3 occupancy GSE10837: Meiotic time course of the trimethylation of the Lysine 4 of Histone H3 (H3K4me3) in a mutant Spo11F GSE10838: Meiotic time course of Histone H3 occupancy in a mutant Spo11F G...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-31 | E-GEOD-11004 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and mei4 knock-out fission yeast to identify genes that are activated during meiosis
To identify genes that are activated during meiosis and tell the effect of mei4 on different genes at 0 and 5 hours after meiotic induction.
ORGANISM(S): Schizosaccharomyces pombe 
2008-09-26 | E-TABM-465 | biostudies-arrayexpress
ProteomicsIn vitro phosphorylation of ASY1 by CDKA;1
Meiosis is a complex cell division program reducing chromosome number as a prerequisite for sexual reproduction and at the same time leading to a new combination of parental alleles contributing to biodiversity. Little is known about how the distinct order of the molecular processes of meiosis are o...
ORGANISM(S): Arabidopsis Thaliana 
2019-10-01 | PXD011335 | panorama
TranscriptomicsTranscriptome Profile of CYC2 K.O. and WT during meiosis in Tetrahymena thermophila
Meiotic recombination is carried out through a specialized pathway for the formation and repair of DNA double-strand breaks (DSBs) made by the Spo11 protein. The present study shed light on the functional role of Cyclin, CYC2, in Tetrahymena thermophila which has transcriptionally high expression le...
ORGANISM(S): Tetrahymena thermophila 
2016-04-06 | E-GEOD-79286 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast meiosis and sporulation
Study of the meiotic transcriptional profile of transcription factor mutants. The transcription factors atf21 and atf31 are highly induced during the meiotic divisions and required for proper spore formation. To identify possible targets of these transcription factors we compared the transcriptional...
ORGANISM(S): Schizosaccharomyces pombe 
2002-08-05 | E-SNGR-4 | biostudies-arrayexpress
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