To elucidate the mechanisms underlying the perturbation of tumor vascularization in Pparb–/– mice we performed matrigel plug assays23. Matrigel containing prostaglandin E2 (PGE2) and basic fibroblast growth factor (FGF-2) was injected subcutaneously into both wild-type and Pparb–/– mice where it for...
ORGANISM(S): Mus musculus