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UnknownTargeting Plasmodium PI(4)K to eliminate malaria.
Not available
S-EPMC3940870 | biostudies-literature
MetabolomicsHigh-Precision Automated Workflow for Urinary Untargeted Metabolomic Epidemiology
Urine is a non-invasive biofluid that is rich in polar metabolites and well-suited for metabolomic epidemiology. However, due to individual variability in health and hydration status, the physiological concentration of urine can differ >15-fold, which can pose major challenges in untargeted LC-MS me...
2021-06-10 | MTBLS2295 | MetaboLights
MetabolomicsUntargeted LC-MS metabolomics for the analysis of micro-scaled extracellular metabolites from hepatocytes
Metabolome analysis in micro physiological models is a challenge due to the low volume of cell culture medium (CCM). Here, we report a LC-MS-based untargeted metabolomics protocol for the detection of hepatocyte extracellular metabolites from micro-scale samples of CCM. Using a single LC-MS method w...
2021-01-04 | MTBLS1794 | MetaboLights
UnknownPhase I Trial of the Human Double Minute 2 Inhibitor MK-8242 in Patients With Advanced Solid Tumors.
Not available
S-EPMC5946729 | biostudies-literature
TranscriptomicsEstablishment and Comparative Characterization of Novel Non-Small Cell Lung Cancer Cell Lines and Their Corresponding Tumor Tissue
Cell lines play an important role for studying tumor biology and novel therapeutic agents. We demonstrated that cell lines represent a useful and reliable in vitro system for studying basic mechanisms in lung cancer. Moreover, we presented 3 novel, comprehensively characterized SCC cell lines. Estab...
ORGANISM(S): Homo sapiens 
2011-08-30 | E-GEOD-25251 | biostudies-arrayexpress
GenomicsChIP-Seq of human endogenous small RNAs associated to Argonaute 1 and 2
Small non-coding RNAs function in concert with Argonaute (Ago) proteins to regulate gene expression at the level of transcription, mRNA stability or translation. Ago proteins bind small RNAs and form the core of silencing complexes. Here we report the analysis of small RNAs associated with human ...
ORGANISM(S): Homo sapiens 
2008-11-20 | E-GEOD-13370 | biostudies-arrayexpress
UnknownChemical Elements and the Quality of Manuka (Leptospermum scoparium) Honey.
Not available
S-EPMC8303644 | biostudies-literature
UnknownPembrolizumab for Platinum- and Cetuximab-Refractory Head and Neck Cancer: Results From a Single-Arm, Phase II Study.
Not available
S-EPMC5946724 | biostudies-literature
TranscriptomicsIdentification of novel Epstein-Barr Virus miRNA genes from Nasopharyngeal Carcinomas
MicroRNAs (miRNAs) represent a conserved class of small non-coding RNAs that are found in all higher eukaryotes as well as some DNA viruses. MiRNAs are 20-25 nucleotides (nt) in length and have important regulatory functions in biological processes such as embryonic development, cell differentiation...
ORGANISM(S): Homo sapiens 
2009-02-07 | E-GEOD-14738 | biostudies-arrayexpress
TranscriptomicsIdentification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68
Murine gammaherpesvirus 68 (MHV-68) is closely related to Epstein-Barr virus (EBV) and KaposiM-bM-^@M-^Ys sarcoma-associated herpesvirus (KSHV) and provides a small animal model to study the pathogenesis of gammaherpesvirus (M-NM-3HV) infections. To completely explore the potential of the MHV-68 sys...
ORGANISM(S): Mus musculus 
2010-07-15 | E-GEOD-22938 | biostudies-arrayexpress
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