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TranscriptomicsPlasmodium berghei PbeIK2KO sporozoites
Malaria sporozoites, the form transmitted by mosquitoes, are quiescent while in the insect salivary glands. It is only after the sporozoites are deposited in the host’s skin, migrate to the liver and infect hepatocytes that the parasites continue the life cycle. We show that the sporozoite latency...
ORGANISM(S): Plasmodium berghei 
2010-05-16 | E-GEOD-16259 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of eight different time periods of the Anopheles gambiae lifecycle
We conducted a genome wide survey of mosquito gene expression profiles during 8 different time periods of the Anopheles gambiae lifecycle. The timeperiods included embryos, E, collected 12-14 hours post oviposition (hpo), five larval samples, La-Le, with La collected approximately 48h hpo and the re...
ORGANISM(S): Anopheles gambiae 
2007-07-19 | E-TABM-186 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of head, midgut, carcass and ovaries of adult Anopheles gambiae mosquitoes
We conducted a genome wide survey of mosquito gene expression profiles in 4 different tissues of adult Anopheles gambiae mosquitoes. The tissues included the head, the midgut, the carcass (corresponding to the remainder of the mosquito after decapitation and midgut removal) and ovaries. Ovaries were...
ORGANISM(S): Anopheles gambiae 
2007-07-19 | E-TABM-153 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human blood lymphoblasts purified at three time points from childhood ALL samples (0h, 6-8h, 24h after treatment with prednisolone
Glucocorticoids (GC) are in most chemotherapy protocols for lymphoid malignancies, particularly childhood acute lymphoblastic leukaemia (ALL) for their ability to induce apoptosis in malignant blast. The underlying mechanism, however, has so far only been investigated in model systems. This study co...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2842 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of thymic mouse cells
Glucocorticoids (GC) are in most chemotherapy protocols for lymphoid malignancies, particularly childhood acute lymphoblastic leukaemia (ALL) for their ability to induce apoptosis in malignant blast. The underlying mechanism, however, has so far only been investigated in model systems. This study co...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2843 | biostudies-arrayexpress
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