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A quantitative surface biotin-labeling approach combined with mass spectrometry was used to identify differentially expressed surface proteins in uveal melanoma (UM) cells, in which RAB1A was either knocked down or overexpressed, compared with the respective controls.
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD069080 | Pride
We previously showed that transgenic enhancement of histamine production in B16-F10 melanomas strongly supports tumor growth in C57Bl/6 mice (Cancer Res, 2005 Pos et al.). In this array experiment, gene expression profiles of transgenic mouse melanomas, secreting different amounts of histamine, were...
ORGANISM(S): Mus musculus 
This is a mathematical model describing the imbalance between T helper (Th1/Th2) cell types in melanome patients, together with its regulation via IL-12 treatment. The model focuses on the interactions between the two T helper cell types as mediated by their respective key cytokines, interferon gamm...
2024-09-02 | BIOMD0000000881 | BioModels
Conjunctival and mucosal melanoma
Liquid biopsies are becoming imperative on early patient diagnosis, prognosis and evaluation of residual disease. The use of circulating extracellular vesicles (EVs) as surrogate markers of tumor progression could be a powerful tool in the clinical setting. EVs in plasma have emerged as a non-invasi...
ORGANISM(S): Homo sapiens (Human) 
2019-03-13 | PXD012042 | Pride
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