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TranscriptomicsSpecific molecular signatures underlie response to decitabine in CMML [RNA-seq]
Myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML) are characterized by mutations in epigenetic modifiers and aberrant DNA methylation. DNA methyltransferase inhibitors (DMTis) are used to treat these disorders, but response is highly variable with few means to predict which patien...
ORGANISM(S): Homo sapiens 
2015-03-31 | E-GEOD-61162 | biostudies-arrayexpress
GenomicsSpecific molecular signatures underlie response to decitabine in CMML [ERRBS]
Myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML) are characterized by mutations in epigenetic modifiers and aberrant DNA methylation. DNA methyltransferase inhibitors (DMTis) are used to treat these disorders, but response is highly variable with few means to predict which patien...
ORGANISM(S): Homo sapiens 
2015-03-31 | E-GEOD-61161 | biostudies-arrayexpress
Genomicsena-DATASET-GR-05-12-2015-13:51:06:366-72 - samples
In this dataset are the data from : - 17 patients studied by WGS - 49 patients studied by WES - 9 (/49) patients studied by RNASeq at 2 time points - the same 9 patients studied by ERRBS at 2 time points
EGAD00001001853 | EGA
GenomicsCMML Collection of WES, WGS, RNA-Seq and ERRBS data
We first performed a comprehensive analysis of the genome of 66 chronic myelomonocytic leukemia cases using whole exome (N=49) or whole genome (N=17) sequencing for paired leukemic-control DNA. Then, we realized serial analysis of whole exome sequence in 17 cases, completed with serial RNA sequencin...
EGAS00001001264 | EGA
GenomicsGustave Roussy CMML Collection DAC
Data Access Committee EGAC00001000342
EGAC00001000342 | EGA
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