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TranscriptomicsTranscription profiling of T. brucei bloodstream and procyclic forms to look at differential expression of membrane-trafficking genes
To look at differential expression of membrane-trafficking genes,
we extracted RNA from exponentially growing cultures of T. brucei
bloodstream (BSF) and procyclic (PCF) forms, labelled and competitively
hybridised the cDNA to the microarray. 8 arrays, representing
6 BSF and 5 PCF bi...
ORGANISM(S): Trypanosoma brucei 
2008-06-26 | E-MEXP-1529 | biostudies-arrayexpress
GenomicsABCA7 haplodeficiency disrupts microglial inflammatory responses and membrane trafficking
ABCA7 haplodeficiency disrupts microglial inflammatory responses and membrane trafficking
PRJNA580442 | ENA
ProteomicsGlycosylation Limits Forward Trafficking of the Tetraspan Membrane Protein PMP22
Peripheral myelin protein 22 (PMP22) is a tetraspan integral membrane protein for which mistrafficking-causing mutations are linked to the inherited peripheral neuropathy, Charcot-Marie-Tooth disease (CMTD). Wild type (WT) PMP22 is an inefficient folder with ~20% of the protein trafficking to the pl...
ORGANISM(S): Homo sapiens (Human) 
2021-04-27 | PXD023091 | Pride
Charcot-marie-tooth disease Protein quality control Peripheral myelin protein 22 Quantitative proteomics Proteostasis Protein folding 
ProteomicsThe interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking: UapA Interactome
Neosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Go...
ORGANISM(S): Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) 
2023-11-21 | PXD043934 | Pride
Er-exit  copii  copi  traffic  fungi  a. nidulans Golgi-bypass  uapa  proximity dependent biotinylation  proteomics 
ProteomicsThe interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking: UapA-DYDY TurboID
Neosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Go...
ORGANISM(S): Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) 
2023-11-21 | PXD043941 | Pride
Er-exit  copii  copi  traffic  fungi  a. nidulans Golgi-bypass  uapa  proximity dependent biotinylation  proteomics 
ProteomicsThe interactome of the UapA transporter reveals putative new players in anterograde membrane cargo trafficking: ΔartA: UapA-TurboID
Neosynthesized plasma membrane (PM) proteins co-translationally translocate to the ER, concentrate at regions called ER-exit sites (ERes) and pack into COPII secretory vesicles which are sorted to the early-Golgi through membrane fusion. Following Golgi maturation, membrane cargoes reach the late-Go...
ORGANISM(S): Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) 
2023-11-21 | PXD043944 | Pride
Er-exit  copii  copi  traffic  fungi  a. nidulans Golgi-bypass  uapa  proximity dependent biotinylation  proteomics 
UnknownMembrane Trafficking Modulation during Entamoeba Encystation.
Not available
S-EPMC5634486 | biostudies-literature
TranscriptomicsUnexpected roles of ATP11B in platinum resistance
Platinum compounds display clinical activity against a wide variety of solid tumors. However, resistance to these agents is a major limitation in cancer therapy. Reduced platinum uptake and increased platinum export are examples of resistance mechanisms that limit the extent of DNA damage. Here, we ...
ORGANISM(S): Homo sapiens 
2013-01-23 | E-GEOD-43694 | biostudies-arrayexpress
UnknownComprehensive knockout analysis of the Rab family GTPases in epithelial cells.
Not available
S-EPMC6548125 | biostudies-literature
Genomics
A CRISPR screen to identify pro-tumorigenic membrane trafficking regulators
PRJNA1499251 | ENA
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