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UnknownRORα modulates semaphorin 3E transcription and neurovascular interaction in pathological retinal angiogenesis.
Not available
S-EPMC5602899 | biostudies-literature
ProteomicsProteomics analysis of plasma-derived exosomes unveils the aberrant complement and coagulation cascades in dermatomyositis/polymyositis
Dermatomyositis and polymyositis (DM/PM) are systemic autoimmune diseases characterized by proximal muscle weakness. The underlying pathogenetic mechanism of this disease remains elusive. Here, using proteomics analysis, a great overlap of differentially expressed plasma exosomal proteins involved i...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037608 | Pride
Dermatomyositis  polymyositis  exosomes  proteomics  complement and coagulation cascades. 
ProteomicsProteomics analysis of plasma-derived exosomes unveils the aberrant complement and coagulation cascades in dermatomyositis/polymyositis
Dermatomyositis and polymyositis (DM/PM) are systemic autoimmune diseases characterized by proximal muscle weakness. The underlying pathogenetic mechanism of this disease remains elusive. Here, using proteomics analysis, a great overlap of differentially expressed plasma exosomal proteins involved i...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037483 | Pride
Dermatomyositis  polymyositis  exosomes  proteomics  complement and coagulation cascades. 
ProteomicsGlobal Phosphoproteomics Reveals Molecular Networks in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic and heterogeneous autoimmune disease for which its treatment and phosphorylation-dependent regulatory mechanism remain elusive. Here, we aim to explore the molecular mechanism of phosphorylation regulation for SLE. We employed high-throughput Phosphop...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD025399 | Pride
Phosproteomics  sle remission stage  sle active stage  kinases  parallel reaction monitoring 
ProteomicsGlobal Phosphoproteomics Reveals Molecular Networks in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic and heterogeneous autoimmune disease for which its treatment and phosphorylation-dependent regulatory mechanism remain elusive. Here, we aim to explore the molecular mechanism of phosphorylation regulation for SLE. We employed high-throughput Phosphop...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD025559 | Pride
Phosproteomics  sle remission stage  sle active stage  kinases  parallel reaction monitoring 
ProteomicsMouse lung proteomics and S-nitrosoproteomics using LC-MS/MS
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by excessive extracellular matrix deposition and impaired tissue repair. S-nitrosoglutathione reductase (GSNOR, encoded by ADH5) is a key enzyme that regulates protein S-nitrosylation by metabolizing S-nitrosoglutathione...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD061250 | Pride
Mouse Lung Lc-ms/ms 
UnknownEfficient synthesis of α-galactosylceramide and its C-6 modified analogs
Not available
S-EPMC9732566 | biostudies-literature
UnknownBufalin Suppresses Migration and Invasion of Hepatocellular Carcinoma Cells Elicited by Poly (I:C) Therapy.
Not available
S-EPMC5927531 | biostudies-literature
TranscriptomicsTranscription profiling of C. elegans reveals heme homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins
Hemes are essential but potentially cytotoxic cofactors that participate in critical and diverse biological processes. Although the pathway and intermediates for heme biosynthesis have been well defined, the intracellular networks which mediate heme trafficking remain unknown. Caenorhabditis e...
ORGANISM(S): Caenorhabditis elegans 
2008-10-18 | E-GEOD-8696 | biostudies-arrayexpress
UnknownChloroplast Phylogenomics Reveals the Intercontinental Biogeographic History of the Liquorice Genus (Leguminosae: Glycyrrhiza).
Not available
S-EPMC7318913 | biostudies-literature
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