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MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
UnknownTissue Distribution and Abundance of the Parasitic Dinoflagellate <i>Hematodinium perezi</i> in Naturally Infected <i>Portunus trituberculatus</i>.
Not available
S-EPMC12301046 | biostudies-literature
MetabolomicsA Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented Brassica napus Bee Pollen

Bee pollen is consumed for its nutritional and pharmacological benefits, but it also contains hazardous allergens which has not been identified. Here, we identified 2 potential allergens, glutaredoxin and oleosin-B2, in Brassica napus (B. napus) bee pollen using mass spectrometr...

2022-03-23 | MTBLS3950 | MetaboLights
UnknownHepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance.
Not available
S-EPMC5434661 | biostudies-literature
ProteomicsIdentification TCF7L2-L, tcf7l2-S and IgG COIP proteins by LC-MS
Identification of binding protein of TCF7L2-L by LC/MS
ORGANISM(S): Homo sapiens (Human) 
2025-01-13 | PXD048102 | Pride
Coip proteins 
ProteomicsProteomic analysis of the physiological response of high CO2 stimulation tetraploid Robinia pseudoacacia L.
When plants are continuously treated with high concentration of CO2, they will show different physiological and biochemical characteristics due to the different conditions of the plants themselves and the environment, and the leaves, as the main organ of gas exchange between plants and the outside w...
ORGANISM(S): Robinia pseudoacacia 
2024-06-16 | PXD047363 | Pride
High co2 Proteomic Stomatal Photosynthesis Respiration Robinia pseudoacacia l. 
TranscriptomicsTranscriptome analysis in Haematococcus pluvialis: astaxanthin induction by salicylic acid (SA) and jasmonic acid (JA)
Haematococcus pluvialis transcriptome analysis The genetic transcriptome details of astaxanthin biosynthesis were analysed by exposing the algal cells to 25 mg/L of SA and JA for 1, 6 and 24 hours, plus to the control (no stress). SRP062153 PRJNA292140
ORGANISM(S): Haematococcus pluvialis 
2016-02-15 | E-GEOD-71986 | biostudies-arrayexpress
UnknownCharacterization of a novel two-component Na+(Li+, K+)/H+ antiporter from Halomonas zhaodongensis.
Not available
S-EPMC5484666 | biostudies-literature
UnknownDifferential compensation of two cyclooxygenases in renal homeostasis is independent of prostaglandin-synthetic capacity under basal conditions.
Not available
S-EPMC6133703 | biostudies-literature
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